ArticleTurk gogus kalp damar cerrahisi dergisi2023
Is decreased tissue elasticity more important than histopathological changes in ruptures of ascending aortic aneurysms?
Article in Turk gogus kalp damar cerrahisi dergisi, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 1 citations in OpenAlex.
- Non-invasive estimation of material properties of normal and dissected human ascending aortasFrontiers in bioengineering and biotechnology · 2025Article
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Authors and funding
8 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Background: In this study, we aimed to investigate the natural properties of ascending aortic aneurysms and to compare dilated aortic tissues of patients with ascending aortic aneurysms and the non-pathological aortic tissues of cadavers. Methods: Between January 2017 and January 2020, a total of 14 patients (12 males, 2 females; mean age: 66.6±8.4 years; range, 54 to 77 years) who underwent elective ascending aortic surgery without genetic disease or family history in the etiology were included in the study. Aortic tissues taken from the patients with ascending aortic aneurysms and cadavers without any aortic pathology were compared histopathologically and biomechanically. An experienced pathologist performed a histological evaluation with appropriate staining and scoring. In the biomechanical examination, stress-strain curves were created with the uniaxial tensile test. The instantaneous elastic modulus was calculated based on the first regions of the curves (Ei) and the slopes of the linear region close to rupturing (Es). Results: In the pathological examination, there was no statistically significant difference in the parameters of both the patient and control groups (p>0.05). In the biomechanical examination, Ei values were significantly higher in the patients with ascending aortic aneurysms, while Es values were comparable between the groups (p=0.028 and p=0.609, respectively). Conclusion: Our study results showed that the tissues of the ascending aortic aneurysm were much more rigid, although no significant histopathological changes were detected. These findings are meaningful in understanding the structure of normal and pathological aortic tissue.
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