Evidence map›Paper›PMID 37484594›Full record

ArticleThe Pan African medical journal2023

A rare presentation of a spinal diffuse midline glioma in a child: a case report.

Zineb Isfaoun, Khadija Laasri, Manal Jidal, Nadia Cherradi, Adil Melhaoui, Latifa Chat, Siham El Haddad, Maria El Kababri, Mohamed El Khorassani, Amina Kili and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Zineb IsfaounMohammed V University, Pediatric Hematology and Oncology Department, Children's Hospital in Rabat, Rabat, Morocco.
Khadija LaasriMohammed V University, Radiology Department, Children's Hospital in Rabat, Rabat, Morocco.
Manal JidalMohammed V University, Radiology Department, Children's Hospital in Rabat, Rabat, Morocco.
Nadia CherradiMohammed V University, Pathology Department, Children's Hospital in Rabat, Rabat, Morocco.
Adil MelhaouiMohammed V University, Neurosurgery Department, Children's Hospital in Rabat, Rabat, Morocco.
Latifa ChatMohammed V University, Radiology Department, Children's Hospital in Rabat, Rabat, Morocco.
Siham El HaddadMohammed V University, Radiology Department, Children's Hospital in Rabat, Rabat, Morocco.
Maria El KababriMohammed V University, Pediatric Hematology and Oncology Department, Children's Hospital in Rabat, Rabat, Morocco.
Mohamed El KhorassaniMohammed V University, Pediatric Hematology and Oncology Department, Children's Hospital in Rabat, Rabat, Morocco.
Amina KiliMohammed V University, Pediatric Hematology and Oncology Department, Children's Hospital in Rabat, Rabat, Morocco.
Naoual El AnsariMohammed V University, Pediatric Hematology and Oncology Department, Children's Hospital in Rabat, Rabat, Morocco.
Laila HessissenMohammed V University, Pediatric Hematology and Oncology Department, Children's Hospital in Rabat, Rabat, Morocco.
Mohammed V University · MA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our patient had an extremely rare type of pediatric Diffuse Midline Glioma (DMG) with modified H3 K27 that occurred in the cervical spinal cord. Due to its location in the spinal cord, slow clinical presentation with torticollis for 7 months, and the non-specific radiological appearance of this tumour, it was initially considered to be a low-grade glioma. Based on imaging findings, the neurosurgery team performed a complete surgical resection, but the pathological features were consistent with a high-grade, diffuse midline glioma. Therefore, we are reporting a case of an altered high-grade DMG H3K27 glioma, which is difficult to diagnose due to its slow clinical symptoms which caused a delay in diagnosis, non-specific imaging, and with difficulty in accessing histopathological markers in low and middle income countries (LMIC).

Indexed as

Brain NeoplasmsGliomaSpinal Cord NeoplasmsChildHistonesHumansMutationNeckHistonescase reportchildDiffuse midline gliomaH3K27 altered

Identifiers

PMID37484594
PMCPMC10362656
OpenAlexW4366406455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.