Evidence map›Paper›PMID 37484549›Full record

ArticleOxford medical case reports2023

A case of eosinophilic granulomatous polyangiitis with concurrent central and peripheral nervous system involvement.

Anusha Challa, Sai Sirisha, Harsh Khandelia, Mihir Parekh, Anuja Patil, Sita Jayalakshmi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Anusha ChallaDepartment of Neurology, Krishna Institute of Medical Sciences, Secunderabad, India.
Sai SirishaDepartment of Neurology, Krishna Institute of Medical Sciences, Secunderabad, India.
Harsh KhandeliaDepartment of Critical Medicine, Krishna Institute of Medical Sciences, Secunderabad, India.
Mihir ParekhDepartment of Neurology, Krishna Institute of Medical Sciences, Secunderabad, India.
Anuja PatilDepartment of Neurology, Krishna Institute of Medical Sciences, Secunderabad, India.ORCID https://orcid.org/0000-0003-2871-6820
Sita JayalakshmiDepartment of Neurology, Krishna Institute of Medical Sciences, Secunderabad, India.
Krishna Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic granulomatous polyangiitis (EGPA) like other antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis has multisystemic involvement. It commonly manifests with prodromal pulmonary involvement as asthma, chronic sinusitis followed by systemic vasculitic complications associated with blood and tissue eosinophilia. Central nervous system manifestations at presentation are uncommon compared with peripheral nervous system involvement. Vasculitic neuropathy in EGPA commonly presents as mononeuritis multiplex but rarely as polyradiculopathy. Late onset EGPA often presents with systemic involvement, and early diagnosis is a key to prevent further complications. The neuropathy in late onset EGPA is often refractory to immunosuppression and corticosteroids treatment. We report a case of EGPA with late onset asthma presenting with acute infarct and demyelinating polyradiculoneuropathy that progressed with bulbar paralysis and profound dysautonomia. This illustrates simultaneous involvement of central and peripheral nervous system with EGPA. Autonomic dysfunction can occur in patients of EGPA with multisystem involvement, which may predict severe complications.

Identifiers

PMID37484549
PMCPMC10359064
OpenAlexW4384833892

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.