Evidence map›Paper›PMID 37484390›Full record

ArticleHeliyon2023

Establishment of

J Vijayalakshmi, Rajesh Kumar Chaurasia, K Satish Srinivas, K Vijayalakshmi, Solomon F D Paul, N N Bhat, B K Sapra

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Dose-response : a publication of International Hormesis Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

J VijayalakshmiDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (DU), Chennai, India.
Rajesh Kumar ChaurasiaRadiological Physics and Advisory Division, Bhabha Atomic Research Centre (BARC), Mumbai, India.
K Satish SrinivasDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (DU), Chennai, India.
K VijayalakshmiDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (DU), Chennai, India.
Solomon F D PaulDepartment of Human Genetics, Sri Ramachandra Institute of Higher Education and Research (DU), Chennai, India.
N N BhatRadiological Physics and Advisory Division, Bhabha Atomic Research Centre (BARC), Mumbai, India.
B K SapraRadiological Physics and Advisory Division, Bhabha Atomic Research Centre (BARC), Mumbai, India.
Sri Ramachandra Institute of Higher Education and Research · INBhabha Atomic Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the modern developing society, application of radiation has increased extensively. With significant improvement in the radiation protection practices, exposure to human could be minimized substantially, but cannot be avoided completely. Assessment of exposure is essential for regulatory decision and medical management as applicable. Until now, cytogenetic changes have served as surrogate marker of radiation exposure and have been extensively employed for biological dose estimation of various planned and unplanned exposures. Dicentric Chromosomal Aberration (DCA) is radiation specific and is considered as gold standard, micronucleus is not very specific to radiation and is considered as an alternative method for biodosimetry. In this study dose response curves were generated for X-ray induced "dicentric + ring" and micronuclei, in lymphocytes of three healthy volunteers [2 females (age 22, 23 years) and 1 male (24 year)]. The blood samples were irradiated with X-ray using LINAC (energy 6 MV, dose rate 6 Gy/min), in the dose range of 0-5Gy. Irradiated blood samples were cultured and processed to harvest metaphases, as per standard procedures recommended by International Atomic Energy Agency. Pooled data obtained from all the three volunteers, were in agreement with Poisson distribution for "dicentric + ring", however over dispersion was observed for micronuclei. Data ("dicentric + ring" and micronuclei) were fitted by linear quadratic model of the expression Y[bond, double bond]C + αD + βD

Indexed as

BiodosimetryDicentrics chromosomal aberrationsDose blinded samplesDose-response curveMicronuclei

Identifiers

PMID37484390
PMCPMC10361230
OpenAlexW4379743369

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.