Evidence map›Paper›PMID 37484241›Full record

ArticleHeliyon2023

The prevalence of latent tuberculosis infection in patients with chronic kidney disease: A systematic review and meta-analysis.

Ayinalem Alemu, Zebenay Workneh Bitew, Getu Diriba, Getachew Seid, Shewki Moga, Saro Abdella, Emebet Gashu, Kirubel Eshetu, Getachew Tollera, Mesay Hailu Dangisso and 1 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Ayinalem AlemuEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Zebenay Workneh BitewSt. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Getu DiribaEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Getachew SeidEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Shewki MogaEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Saro AbdellaEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Emebet GashuAddis Ababa Health Bureau, Addis Ababa, Ethiopia.
Kirubel EshetuUSAID Eliminate TB Project, Management Sciences for Health, Addis Ababa, Ethiopia.
Getachew TolleraEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Mesay Hailu DangissoEthiopian Public Health Institute, Addis Ababa, Ethiopia.
Balako GumiAklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.
Ethiopian Public Health Institute · ETAddis Ababa City Administration Health Bureau · ETAddis Ababa University · ETSt. Paul's Hospital Millennium Medical College · ET

Funding

Ethiopia-Emory TB Research Training ProgramD43TW009127 · FIC · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Kidist Bobosha · 2013 to 2026
$3.4M
FIC NIH HHS D43 TW009127
6 · The paper itself

Abstract

Objective: To estimate the prevalence of latent tuberculosis infection (LTBI) in chronic kidney disease (CKD) patients Methods: This study was conducted following the PRISMA guidelines. We identified, 3694 studies from the whole search, and 59 studies were included. Each study's quality was assessed using JBI checklist. We employed STATA version 17 for statistical analysis. We assessed heterogeneity using I Results: The pooled prevalence of LTBI among CKD patients using data collected from 53 studies having 12,772 patients was 30.2% (95%CI; 25.5, 34.8). The pooled prevalence among pre-dialysis, hemodialysis, peritoneal dialysis, and renal transplanted patients was 17.8% (95%CI; 3.3, 32.4), 34.8% (95%CI; 29.1, 40.5), 25% (95%CI; 11, 38), and 16% (95%CI; 7, 25), respectively. The pooled prevalence of LTBI stratified by the laboratory screening methods was 25.3% (95%CI: 20.3-30.3) using TST, 28.0% (95%CI; 23.9-32.0) using QFT, and 32.6%, (95%CI: 23.7-41.5) using T-SPOT. Conclusion: There is high prevalence of LTBI among CKD patients mainly in patients on dialysis. Thus, early diagnosis and treatment of LTBI in CKD patients should be performed to prevent active TB in CKD patients.

Indexed as

Chronic kidney diseaseDialysisHemodialysisLatent tuberculosisPeritoneal dialysisRenal transplant

Identifiers

PMID37484241
PMCPMC10361307
OpenAlexW4380200820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.