Evidence map›Paper›PMID 37483881›Full record

ArticlePalliative medicine reports2023

Termination of Palliative Chemotherapy Near the End of Life: A Retrospective Study of Gastrointestinal Cancer Patients.

Yoshifumi Matsumoto, Akito Higuchi, Marika Shiba, Kenta Sasaki, Takuro Saiki, Yujiro Honma, Kazuyoshi Kimura, Qiliang Zhou, Yasuo Saijo

Abstract read
In one paragraph

Article in Palliative medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yoshifumi MatsumotoDepartment of Medical Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Akito HiguchiSchool of Medicine, Niigata University, Niigata, Japan.
Marika ShibaSchool of Medicine, Niigata University, Niigata, Japan.
Kenta SasakiDepartment of Medical Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Takuro SaikiDepartment of Medical Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Yujiro HonmaDepartment of Medical Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Kazuyoshi KimuraDepartment of Medical Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Qiliang ZhouDepartment of Medical Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Yasuo SaijoDepartment of Medical Oncology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Palliative chemotherapy is commonly used for advanced cancer patients. The timing of chemotherapy termination is crucial for efforts to maintain quality of life. Patients and Methods: This retrospective study included gastrointestinal cancer patients who were treated with chemotherapy and died between 2013 and 2022 at Niigata University Medical and Dental Hospital. Data were reviewed regarding age, gender, cancer type, reason for chemotherapy termination, cause of death, survival after chemotherapy termination, and place of death. Results: In total, 388 patients were included; the median survival after chemotherapy was 73 days. Patients aged <67 years had shorter survival durations (59 days), compared with patients aged >67 years (82 days). Ten (2.6%) patients began a new chemotherapy regimen, whereas 17 (4.4%) patients received chemotherapy, within 4 weeks before death. The most common reason for chemotherapy termination was disease progression, and most deaths occurred in hospitals. Conclusion: The rates of chemotherapy and initiation of new chemotherapeutic regimens near the end of life were lower than previously reported. Most deaths occurred in hospitals, highlighting the need for development of hospices.

Indexed as

chemotherapyend of lifegastrointestinal cancertermination

Identifiers

PMID37483881
PMCPMC10357107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.