ArticleAddiction neuroscience2023
Appetitive and aversive cue reactivities differentiate neural subtypes of alcohol drinkers.
Article in Addiction neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What can case-control comparisons of neural drug cue reactivity tell us about addiction? A neuroimaging meta-analysis.Translational psychiatry · 2026Pooled it
- Real-world alcohol cue exposure and drinking risk in alcohol use disorder.Translational psychiatry · 2026Article
- The effects of polygenic risks for alcohol misuse on negative emotion processing in young adult binge drinkers.Translational psychiatry · 2025Article
- Intrinsic connectivity demonstrates a shared role of the posterior cingulate for cue reactivity in both gambling and cocaine use disorders.Addictive behaviors · 2024Article
- Functional Networks of Reward and Punishment Processing and Their Molecular Profiles Predicting the Severity of Young Adult Drinking.Brain sciences · 2024Article
- Neural correlates of increased alcohol demand following alcohol cue exposure in adult heavy drinkers.Psychiatry research. Neuroimaging · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Craving reflects the subjective urge to use drugs and can be triggered by both positive and negative emotional states. No studies have systematically investigated the relative roles of these mechanisms in the pathophysiology of substance misuse. Here, we performed meta-analyses of drug cue-elicited reactivity and win and loss processing in the monetary incentive delay task to identify distinct neural correlates of appetitive and aversive responses to drug cues. We then characterized the appetitive and aversive cue responses in seventy-six alcohol drinkers performing a cue craving task during fMRI. Imaging data were processed according to published routines. The appetitive circuit involved medial cortical regions and the ventral striatum, and the aversive circuit involved the insula, caudate and mid-cingulate cortex. We observed a significant correlation of cue-elicited activity (
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