Evidence map›Paper›PMID 37483485›Full record

ArticleFrontiers in oncology2023

Predictive factors and clinicopathological characteristics of outcome in poorly differentiated thyroid carcinoma: a single-institution study.

Zheng Wan, Bing Wang, Jing Yao, Qing Li, Xin Miao, Yanbing Jian, Sisi Huang, Shengwei Lai, Chen Li, Wen Tian

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Zheng WanDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Bing WangDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Jing YaoDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Qing LiDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Xin MiaoDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Yanbing JianDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Sisi HuangDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Shengwei LaiDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Chen LiDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Wen TianDepartment of Thyroid & Hernia Surgery, Medical Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing, China.
Chinese People's Liberation Army · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To elucidate the clinicopathological characteristics and prognostic factors of poorly differentiated thyroid carcinoma. Method: A total of 24912 thyroid carcinoma patients admitted to the First Medical Center of Chinese People's Liberation Army General Hospital from 2005 to 2020 were retrospectively reviewed. A total of 94 patients (39 males and 55 females, a male-female ratio of 1:1.4) fulfilled the selection criteria. Of these, 73 patients had undergone surgery. The clinical and pathological data were collected from each enrolled patient. Univariate and multivariate Cox regression analyses were performed to determine independent prognostic factors. All analyses were performed with the SPSS version 26.0 and R version 1.2.5033 in the R Studio environment. Results: The specimens included 20 cases of poorly differentiated thyroid carcinoma complicated with papillary thyroid carcinoma, 17 cases complicated with follicular thyroid carcinoma, 34 cases complicated with other pathological types and 23 with a separate entity. The patient demonstrated a large age span, median age was 57 years (range 8-85 years, average 55.20 ± 15.74 years). The survival time of the 94 cases was calculated, and the mean Overall survival time was 33 (range, 1-170) months, and the mean Recurrence-free survival time was 14 (range, 1-90) months. Recurrence-free mortality is related to the age at diagnosis, extrathyroidal extension and Associated thyroid cancer (p<0.05). In contrast, overall mortality is related to the age at diagnosis, sex, extrathyroidal extension, T stage (AJCC 8th), surgery and radiation (p<0.05). Conclusion: Middle-aged and elderly patients are still at high risk for poorly differentiated thyroid carcinoma. The pathologic results of poorly differentiated thyroid carcinoma are varied, and reasonable treatment has an important impact on the prognosis of poorly differentiated thyroid carcinoma.

Indexed as

cancer specific survivaldecision curve analysisoverall survivalpoorly differentiated thyroid carcinomarecurrence-free survivalX-tile

Identifiers

PMID37483485
PMCPMC10361777
OpenAlexW4383499344

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.