Evidence map›Paper›PMID 37483461›Full record

ArticleCase reports in neurology

Encephalitis as a Clinical Manifestation of COVID-19: A Case Series.

Muhammad Hammad Sharif, Madeeha Khaleeque, Asad Ali Khan, Muhammad Hassan Jan, Atif Ahmed, Nida Latif, Abdul Qadir, Muhammad Hanif, Amjid Iqbal

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Muhammad Hammad SharifDepartment of Cardiology, Hayatabad Medical Complex, Peshawar, Pakistan.
Madeeha KhaleequeDepartment of Cardiology, Hayatabad Medical Complex, Peshawar, Pakistan.
Asad Ali KhanDepartment of Cardiology, Hayatabad Medical Complex, Peshawar, Pakistan.
Muhammad Hassan JanDepartment of Medicine, Hayatabad Medical Complex, Peshawar, Pakistan.
Atif AhmedDepartment of Medicine, Khyber Teaching Hospital, Peshawar, Pakistan.
Nida LatifDepartment of Medicine, Hayatabad Medical Complex, Peshawar, Pakistan.
Abdul QadirDepartment of Medicine, Naseer Teaching Hospital, Peshawar, Pakistan.
Muhammad HanifDepartment of Medicine, Hayatabad Medical Complex, Peshawar, Pakistan.
Amjid IqbalDepartment of Radiology, Ayub Teaching Hospital, Abbottabad, Pakistan.
Hayatabad Medical Complex · PKKhyber Teaching Hospital · PKAyub Medical College · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is a novel virus which causes a variety of clinical manifestations in the body, some of which are yet to be discovered. The main aim of our study is to highlight the neurological manifestations of COVID-19 as it is still new to the medical world, and to emphasize the fact that the physicians have to be wary of the possibility that patients affected by COVID-19 can present with encephalitis. Only a few studies are available so far regarding the neurological manifestations of this novel virus which highlights the need for this study. We present a case series of 4 patients who were found to have COVID-19 encephalitis. There is still no disease-defining test for diagnosis so the mainstay of diagnosis is exclusion of all the common causes of encephalitis. Brain magnetic resonance imaging and cerebrospinal fluid analysis performs an ancillary in the diagnostic tools. Our study also supports the use of IV tocilizumab (4-8 mg/kg) and IV methylprednisolone (0.5-2 mg/kg) as possible treatment options with good results, as the patients described in our case series responded well to these medications.

Indexed as

Case reportCorticosteroidsCOVID-19EncephalitisNeurological manifestationsTocilizumab

Identifiers

PMID37483461
PMCPMC10359675
OpenAlexW4380854181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.