Evidence map›Paper›PMID 37483443›Full record

SynthesisFrontiers in neurology2023

Repetitive transcranial magnetic stimulation for cerebellar ataxia: a systematic review and meta-analysis.

Lianjun Yin, Xiaoyu Wang, Lianghua Chen, Dandan Liu, Haihong Li, Zhaoxing Liu, Yong Huang, Junqi Chen

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lianjun YinRehabilitation Medicine, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Xiaoyu WangDepartment of Tuina, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Lianghua ChenRehabilitation Medicine, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Dandan LiuRehabilitation Medicine, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Haihong LiRehabilitation Medicine, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Zhaoxing LiuSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Yong HuangSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China.
Junqi ChenRehabilitation Medicine, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China.
Third Affiliated Hospital of Southern Medical University · CNSouthern Medical University · CNFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Repetitive transcranial magnetic stimulation, a non-invasive brain stimulation technique, can manage cerebellar ataxia (CA) by suppressing cerebral cortical excitability. Hence, this study aimed to summarize the efficacy and safety of rTMS for CA patients by meta-analysis. Methods: The PubMed, Embase, Web of Science, and Cochrane Library databases were searched for eligible studies published till 20 May 2023. Weighted mean difference (MD) and 95% confidence intervals (CIs) were used to assess the effect of rTMS treatment. Additionally, the quality of the included studies and the risk of bias were evaluated using the Physiotherapy Evidence Database (PEDro) scale. Results: Overall, eight studies involving 278 CA patients were included in this meta-analysis. rTMS could significantly improve the Scale for the Assessment and Rating of Ataxia (SARA) (MD: -2.00; 95% CI: -3.97 to -0.02, Conclusion: This meta-analysis provides limited evidence that rTMS may be beneficial in treating CA patients. However, these findings should be treated with caution due to the limitations of the smaller sample size and the inconsistent approach and target of rTMS treatment. Therefore, more large-scale RCTs are required to further validate our analytical findings. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=295726, identifier: CRD42022295726.

Indexed as

cerebellar ataxiameta-analysismotor functionsrepetitive transcranial magnetic stimulationsystematic review

Identifiers

PMID37483443
PMCPMC10360185
OpenAlexW4383534108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.