Evidence map›Paper›PMID 37483430›Full record

ArticleOpen life sciences2023

Genetic alterations of

Jianbo Peng, Shuo Fang, Meisheng Li, Yuxin Liu, Xiaolu Liang, Zuobiao Li, Gaohui Chen, Lijiao Peng, Nianping Chen, Lei Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Open life sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Jianbo PengFoshan Traditional Chinese Medicine Hospital, Guangdong, 518000, China.
Shuo FangDepartment of Oncology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong, 518000, China.
Meisheng LiFoshan First People's Hospital, Guangdong, 518000, China.
Yuxin LiuGuangdong Medical University, Zhanjiang, Guangdong, 524000, China.
Xiaolu LiangDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524000, China.
Zuobiao LiDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524000, China.
Gaohui ChenGuangdong Medical University, Zhanjiang, Guangdong, 524000, China.
Lijiao PengDepartment of Oncology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524000, China.
Nianping ChenDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524000, China.
Lei LiuAffiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524000, China.
Xiaohong XuDepartment of Ultrasound, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524000, China.
Wei DaiDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524000, China.
Guangdong Medical College · CNFirst People's Hospital of Foshan · CNFoshan Hospital of TCM · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to investigate certain genetic features of intrahepatic cholangiocarcinoma (ICCA). A total of 12 eligible ICCA patients were enrolled, and tumor tissues from the patients were subjected to next-generation sequencing of a multi-genes panel. Tumor mutation burden (TMB), mutated genes, copy number variants (CNVs), and pathway enrichment analysis were performed. The median TMB was 2.76 Mutation/Mb (range, 0-36.62 Mutation/Mb) in ICCA patients. The top two most commonly mutated genes in ICCA were

Indexed as

genetic profileintrahepatic cholangiocarcinomanext-generation sequencingprognosis analysistumor mutation burden

Identifiers

PMID37483430
PMCPMC10358752
OpenAlexW4384787080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.