ArticleESC heart failure2023
Effects of septal myectomy on left atrial and left ventricular function in obstructive hypertrophic cardiomyopathy.
Article in ESC heart failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 15 citations in OpenAlex.
- Serial Changes in Ventricular Strain in Symptomatic Obstructive Hypertrophic Cardiomyopathy Treated With Mavacamten: Insights From the VALOR-HCM Trial.Circulation. Cardiovascular imaging · 2024Trial
- Four-Chamber Deformation Remodeling and Atrial Fibrillation After Septal Myectomy for Obstructive Hypertrophic Cardiomyopathy.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Imaging-Based Risk Stratification for Sudden Cardiac Death in Hypertrophic Cardiomyopathy: Current Evidence and Clinical Perspectives.Medical sciences (Basel, Switzerland) · 2026Review
- Left atrial dysfunction in different morphologic phenotypes of hypertrophic cardiomyopathy: a cardiac magnetic resonance feature tracking study.Quantitative imaging in medicine and surgery · 2026Article
- Alcohol Septal Ablation in Hypertrophic Obstructive Cardiomyopathy: Long-Term Follow-Up of Deformations and Hemodynamics.Journal of magnetic resonance imaging : JMRI · 2026Article
- Optimizing imaging techniques in hypertrophic cardiomyopathy: challenges and opportunities.European heart journal. Imaging methods and practice · 2026Review
- Heart Failure in the Modern Era: A Narrative Overview of Recent Research from 2022-2025.Journal of cardiovascular development and disease · 2025Review
- Real-World Observations in Patients With Obstructive Hypertrophic Cardiomyopathy Treated With Mavacamten: Evidence of Favorable Disease Modification.Journal of the American Heart Association · 2025Observational
- Favorable cardiac remodeling in response to treatment in obstructive hypertrophic cardiomyopathy: a current appraisal.Future cardiology · 2025Review
- Atrial cardiomyopathy.ESC heart failure · 2025Article
- Echocardiographic Changes Following Surgical Myectomy in Severely Symptomatic Obstructive Hypertrophic Cardiomyopathy: Insights From the SPIRIT-HCM Study.Journal of the American Heart Association · 2025Observational
- Atrial remodelling and dysfunction in hypertrophic cardiomyopathy: prognostic role and therapeutic target.Frontiers in cardiovascular medicine · 2025Review
- Early left atrial reverse remodelling in patients with hypertrophic obstructive cardiomyopathy receiving transapical beating-heart septal myectomy.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Effects of septal myectomy on left atrial and left ventricular function in obstructive hypertrophic cardiomyopathy.ESC heart failure · 2023Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
aimsMechanical function of the left atrium (LA) and the left ventricle (LV) has been demonstrated to be a prognostic factor in patients with hypertrophic cardiomyopathy (HCM). We explore whether myocardial mechanical function can be improved by septal reduction therapy in symptomatic obstructive HCM. METHODS AND
resultsAmong 65 patients who underwent septal myectomy for symptomatic obstructive HCM from 2006 to 2022, 44 were analysed after excluding those who underwent simultaneous valve repair or replacement or maze operation. LA and LV functional variables including LA strain and LV global longitudinal strain were evaluated by two-dimensional and speckle-tracking echocardiography and compared before and 1 year after surgery. After septal myectomy, LA volume index (58.1 ± 18.3 vs. 45.3 ± 14.6 mL/m
conclusionsAs haemodynamic loads due to LV outflow tract obstruction was relieved through surgical septal reduction therapy in patients with symptomatic obstructive HCM, there was a significant reduction in LA volume and restoration of LA mechanical dysfunction. However, LV mechanical dysfunction deteriorated even after surgical septal reduction therapy.
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