Evidence map›Paper›PMID 37482955›Full record

ReviewHematological oncology2024

Personalised therapy in follicular lymphoma - is the dial turning?

Kim M Linton, Lena Specht, Astrid Pavlovsky, Carrie A Thompson, Eva Kimby, Daphne de Jong, Loretta J Nastoupil, Anne-Ségolène Cottereau, Carla Casulo, Clémentine Sarkozy and 1 more

Abstract readReview
In one paragraph

Review in Hematological oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kim M LintonDepartment of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.ORCID https://orcid.org/0000-0002-3294-1548
Lena SpechtDepartment of Oncology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-6902-2190
Astrid PavlovskyDepartment of Hematology, Fundaleu Clinical Research Center, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-2068-3721
Carrie A ThompsonDepartment of Internal Medicine, Division of Hematology, Mayo Clinic, Rochester, Minnesota, USA.ORCID https://orcid.org/0000-0002-4518-2309
Eva KimbyDepartment of Medicine Karolinska Institutet, Center of Hematology, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-3078-6131
Daphne de JongDepartment of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID https://orcid.org/0000-0002-9725-4060
Loretta J NastoupilDepartment of Lymphoma/Myeloma, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID https://orcid.org/0000-0001-6071-8610
Anne-Ségolène CottereauDepartment of Nuclear Medicine, Cochin Hospital, APHP, University of Paris Cité, Paris, France.ORCID https://orcid.org/0000-0002-4805-4564
Carla CasuloDepartment of Medicine, University of Rochester, Rochester, New York, USA.ORCID https://orcid.org/0000-0003-4998-9932
Clémentine SarkozyHematology Department, Institut Curie, Saint Cloud, France.ORCID https://orcid.org/0000-0002-1942-9304
Jessica OkosunCentre for Haemato-Oncology Barts Cancer Institute, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0001-6021-5044

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular lymphoma is the most common indolent lymphoma accounting for approximately 20%-25% of all new non-Hodgkin lymphoma diagnoses in western countries. Whilst outcomes are mostly favorable, the spectrum of clinical phenotypes includes high-risk groups with significantly inferior outcomes. This review discusses recent updates in risk stratification and treatment approaches from upfront treatment for limited and advanced stage follicular lymphoma to the growing options for relapsed, refractory disease with perspectives on how to approach this from a personalized lens. Notable gaps remain on how one can precisely and prospectively select optimal treatment for patients based on varying risks, with an anticipation that an increased understanding of the biology of these different phenotypes and increasing refinement of imaging- and biomarker-based tools will, in time, allow these gaps to be closed.

Indexed as

Lymphoma, FollicularPrecision MedicineDisease ManagementHumansfollicular lymphomaimmunochemotherapypersonalized therapyPOD24risk factors

Identifiers

PMID37482955
PMCPMC11590056

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.