ArticleAnnals of biomedical engineering2023
Bilateral Asymmetry in Knee and Hip Musculoskeletal Loading During Stair Ascending/Descending in Individuals with Unilateral Mild-to-Moderate Medial Knee Osteoarthritis.
Article in Annals of biomedical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- A systematic comparative analysis of gait characteristics in patients undergoing total knee arthroplasty and unicompartmental knee arthroplasty: a review study.Journal of orthopaedic surgery and research · 2024Pooled it
- Feasibility and Biomechanical Effects of Dynamic Neuromuscular Stabilization Training During Stair Negotiation in Middle-Aged Women with Knee Osteoarthritis: A Randomized Controlled Pilot Study.Journal of functional morphology and kinesiology · 2026Article
- Wearable Sensor-Derived Gait Parameters Across Self-Reported Physical Activity Levels in Individuals With Knee Osteoarthritis and Healthy Controls: Pilot Cross-Sectional Validation Study.JMIR formative research · 2026Article
- Neuromuscular and Kinematic Strategies During Step-Up and Down-Forwards Task in Individuals with Knee Osteoarthritis.Journal of clinical medicine · 2026Article
- Step-down biomechanics in unilateral patellofemoral pain: a cross-sectional study of young females.BMC sports science, medicine & rehabilitation · 2026Article
- Gait and plantar pressure changes after medial open-wedge high tibial osteotomy combined with arthroscopic partial meniscectomy.Frontiers in bioengineering and biotechnology · 2026Article
- The effect of fear of movement on gait characteristics in patients with knee osteoarthritis.BMC musculoskeletal disorders · 2025Article
- Artificial intelligence-based analysis of lower limb muscle mass and fatty degeneration in patients with knee osteoarthritis and its correlation with Knee Society Score.International journal of computer assisted radiology and surgery · 2025Article
- Thigh muscle features in female patients with severe knee osteoarthritis: a cross-sectional study.BMC musculoskeletal disorders · 2025Article
- AI-driven universal lower-limb exoskeleton system for community ambulation.Science advances · 2024Article
- Muscle activation patterns and gait changes in unilateral knee osteoarthritis patients: a comparative study with healthy controls.Clinical rheumatology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Most cases of unilateral knee osteoarthritis (OA) progress to bilateral OA within 10 years. Biomechanical asymmetries have been implicated in contralateral OA development; however, gait analysis alone does not consistently detect asymmetries in OA patient gait. Stair ambulation is a more demanding activity that may be more suited to reveal between-leg asymmetries in OA patients. The objective of this study was to investigate the between-leg biomechanical differences in patients with unilateral mild-to-moderate knee OA. Sixteen unilateral mild-to-moderate medial knee OA patients and 16 healthy individuals underwent kinematic and kinetic analysis of stair ascent and descent. Stair ascent produced higher loading and muscle forces in the unaffected limb compared to the OA limb, and stair descent produced lower loading on the OA limb compared to healthy subjects. These biomechanical differences were apparent in the ankle, knee, and hip joints. The implications of these findings are that OA patients rely more heavily on their unaffected sides than the affected side in stair ascent, a strategy that may be detrimental to the unaffected joint health. The reduction in affected limb loading in stair descent is thought to be related to minimizing pain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.