ReviewThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2023
Perioperative Anxiety and Depression in Older Adults: Epidemiology and Treatment.
Review in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Peri-operative mental health interventions for surgical oncology patients: a narrative synthesis and meta-analysis.Anaesthesia · 2025Pooled it
- The impact of compassion-based interventions on perioperative anxiety and depression: A systematic review and meta-analysis.Journal of affective disorders · 2024Pooled it
- Perioperative Depression and Anxiety Care in Older Patients: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Clinical efficacy and quality of life in elderly patients with lumbar degenerative disease treated with TLIF combined with unilateral pedicle screw fixation: a randomized controlled study.Journal of orthopaedic surgery and research · 2025Trial
- Feasibility, acceptability, and preliminary estimates of a multimodal AKTIVER Heart Delirium Prevention Program in patients indicated for cardiac surgery: study protocol of a randomized controlled PREVENT POstoperative Delirium (PREVENT-POD) Pilot Study.Pilot and feasibility studies · 2026Article
- Biomolecular Pathways Linking Preoperative Chronic Stress to Postoperative Cardiovascular Dysfunction in Noncardiac Surgery.Biomolecules · 2026Review
- Perioperative neurocognitive disorders in older patients: a narrative review of current knowledge in 2026.Perioperative medicine (London, England) · 2026Review
- The association between preoperative telomere length and acute postoperative depression: a single-center prospective observational pilot study.BMC anesthesiology · 2026Observational
- The Effect of Comfort Nursing in Operating Room on Anxiety Depression and Postoperative Recovery in Thyroidectomy Patients With Coexisting Sleep Disorders.Actas espanolas de psiquiatria · 2026Article
- Perioperative Anxiety in Adults: A Narrative Review of Pathophysiology, Assessment, and Multimodal Management Strategies.Healthcare (Basel, Switzerland) · 2026Review
- Integrating Mental Health Into Surgical Care: A Qualitative Study of a Perioperative Mental Health Intervention.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026Article
- Long-term risk of depression after sevoflurane versus propofol anesthesia: a global propensity score-matched cohort study.Translational psychiatry · 2026Article
- Health-Related Quality of Life of Patients With Infective Endocarditis-A Cross-Sectional Study Based on Data From the DERIVE Cohort.Open forum infectious diseases · 2026Article
- Day Surgery in Older Adults: Safety, Effectiveness, and Best Practices for Patient Selection and Perioperative Care-A Narrative Review.Geriatrics (Basel, Switzerland) · 2026Review
- Article
- Considering mental function for successful total knee arthroplasty in older people.World journal of methodology · 2026Article
- Fuzzy boundaries between physical and emotional triggers in Takotsubo syndrome: a scoping review.BMC cardiovascular disorders · 2026Article
- Recovery Experiences of Older Adults and Their Caregivers After Major Elective Noncardiac Surgery.JAMA network open · 2026Article
- Designing a Culturally Adapted Perioperative Mental Health Intervention for Older Black Male Surgical Patients: A Community-Based Participatory Study.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2026Article
- Predictive Modeling of Preoperative Sleep Disorder Risk in Older Adults by Using Data From Wearable Monitoring Devices: Prospective Cohort Study.JMIR formative research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The intervals before and after major surgery is a high-risk period for older adults; in this setting, anxiety and depression are common and serious problems. We comprehensively reviewed current evidence on perioperative anxiety and depression in older adults, focusing on epidemiology, impact, correlates, medication risks, and treatment. Principles of perioperative mental healthcare are proposed based on the findings. Prevalence estimates of clinically significant anxiety and depression range from 5% to 45% for anxiety and 6% to 52% for depression, depending on surgical populations and measurement tools. Anxiety and depression may increase risk for surgical complications and reduce patient participation during rehabilitation. Medical comorbidities, pain, insomnia, cognitive impairment, and delirium are common co-occurring problems. Concomitant uses of central nervous system acting medications (benzodiazepines, anticholinergics, and opioids) amplify the risks of delirium and falls. Based on these findings, we propose that anxiety and depression care should be part of perioperative management in older adults; components include education, psychological support, opioid-sparing pain management, sleep management, deprescribing central nervous system active medications, and continuation and optimization of existing antidepressants. More research is needed to test and improve these care strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.