Evidence map›Paper›PMID 37481906›Full record

ArticleComputer methods and programs in biomedicine2023

Exact inference around ordinal measures of association is often not exact.

Alan D Hutson, Han Yu

Abstract read
In one paragraph

Article in Computer methods and programs in biomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alan D HutsonRoswell Park Cancer Institute, Department of Biostatistics and Bioinformatics, Elm and Carlton Streets, Buffalo, NY 14623, United States. Electronic address: alan.hutson@roswellpark.org.
Han YuRoswell Park Cancer Institute, Department of Biostatistics and Bioinformatics, Elm and Carlton Streets, Buffalo, NY 14623, United States.

Funding

Statistics CoreU10CA180822 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI James J. Dignam · 2014 to 2026
$146.4M
Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI CANDACE S JOHNSON · 1985 to 2026
$116.6M
Immuno-Oncology Translation Network: Data Management and Resource-Sharing Center at RPCIU24CA232979 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI HUTSON, ALAN DAVID, LIU, SONG · 2018 to 2024
$8.9M
YAP1 and RB1 cooperate to regulate lung cancer lineage plasticity and therapeutic resistanceU24CA274159 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI DAVID W. GOODRICH, Alan David Hutson · 2022 to 2026
$8.5M
NCI NIH HHS P30 CA016056NCI NIH HHS U10 CA180822NCI NIH HHS U24 CA232979NCI NIH HHS U24 CA274159
6 · The paper itself

Abstract

In this paper, we build upon the work of DiCiccio and Romano (2017) by extending their permutation test approach, based on the Pearson correlation coefficient in the continuous case, to ordinal measures of association. We investigate commonly used ordinal measures such as the Spearman correlation, Kendall's tau-b, and gamma, which are widely implemented in commercial and open-source software packages for exact testing routines based on generalized hypergeometric probabilities. Similar to DiCiccio and Romano's method, we apply studentization to correct the test statistic, which yields asymptotically valid inference for testing no ordinal association. We present a comprehensive theoretical framework for our approach, followed by a simulation study. Furthermore, we use toy examples to highlight the differences between the exact tests and the asymptotically valid tests. Our findings align with those of DiCiccio and Romano, indicating that exact permutation tests based on ordinal measures of association are often not exact, whereas the asymptotically correct tests perform well for moderate to large sample sizes.

Indexed as

SoftwareComputer SimulationProbabilitySample SizeContingency tableGamma coefficientKendall’S tau-bPearson correlationPermutation testingSpearman correlation

Identifiers

PMID37481906
PMCPMC10528505

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.