SynthesisThe American journal of cardiology2023
Safety and Effectiveness of Adjunctive Posterior Wall Isolation in Atrial Fibrillation Patients: An Updated Meta-Analysis.
Synthesis in The American journal of cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 7 citations in OpenAlex.
- Anatomical and electrophysiological characteristics of the intra-atrial membranous structure in a patient with cor triatriatum sinister undergoing atrial fibrillation catheter ablation.HeartRhythm case reports · 2026Article
- Adjunctive posterior wall isolation for patients with persistent atrial fibrillation: A systematic review and meta-analysis.Heart rhythm O2 · 2025Article
- Left Atrial Posterior Wall Isolation with Pulsed Field Ablation in Persistent Atrial Fibrillation.Journal of clinical medicine · 2023Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
As the atrial fibrillation (AF) recurrence rate remains high after pulmonary vein isolation (PVI), additional left atrial posterior wall isolation (PWI) has been studied in randomized controlled trials, however, the results are conflicting. We performed an updated meta-analysis by searching online databases for the randomized controlled trials comparing the PWI + PVI group to the PVI alone group in patients with AF. The outcomes of interest were AF recurrence, all atrial arrhythmia recurrence, and atrial flutter/atrial tachycardia (AT) recurrence. Risk ratio (RR) with a 95% confidence interval (CI) was estimated using a random effects model. A total of 1,612 patients, with 807 in the PWI + PVI group and 805 in the PVI alone group were included. The mean age was 60 (9) years, 75% were men and 71% had persistent AF. The PWI + PVI group had lower AF recurrence as compared with the PVI alone group (25% vs 32%, RR 0.73, 95% CI 0.56 to 0.96, p = 0.02). There were no significant differences in all atrial arrhythmia recurrence (RR 0.90, 95% CI 0.78 to 1.04, p = 0.16), atrial flutter/AT recurrence (RR 1.19, 95% CI 0.92 to 1.55, p = 0.19) or adverse event rates in the 2 groups (36 vs 31; RR 1.09, 95% CI 0.67 to 1.77, p = 0.73). In conclusion, adjunctive PWI in addition to PVI can be achieved with lower AF recurrence but with a nonsignificant increase in atrial flutter/AT recurrence, resulting in an overall similar rate of all atrial arrhythmia recurrence without increasing the risk of adverse events, when compared with PVI alone strategy.
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