Evidence map›Paper›PMID 37481761›Full record

ArticleCalcified tissue international2023

SLICC-Frailty Index and Its Association with Low Bone Mineral Density and Vertebral Fractures in Women with Systemic Lupus Erythematosus.

Claudia Mendoza-Pinto, Ivet Etchegaray-Morales, Pamela Munguía-Realpozo, Socorro Méndez-Martínez, Jorge Ayón-Aguilar, Francisco Arellano-Avendaño, Álvaro Joaquín Montel-Jarquín, Mario García-Carrasco

Erratum issuedOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Calcified tissue international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Claudia Mendoza-Pinto *Systemic Autoimmune Diseases Research Unit, Specialties Hospital UMAE- CIBIOR, Mexican Institute for Social Security, Puebla, Puebla, Mexico.ORCID http://orcid.org/0000-0002-5101-7705
Ivet Etchegaray-Morales *Department of Rheumatology, Medicine School, Meritorious Autonomous University of Puebla, Puebla, Mexico.ORCID http://orcid.org/0000-0002-5857-4299
Pamela Munguía-RealpozoSystemic Autoimmune Diseases Research Unit, Specialties Hospital UMAE- CIBIOR, Mexican Institute for Social Security, Puebla, Puebla, Mexico. pamela.munguia@yahoo.com.mx.ORCID http://orcid.org/0000-0002-6967-7939
Socorro Méndez-MartínezResearch in Health Coordination, Mexican Social Security Institute, Puebla, Mexico.ORCID http://orcid.org/0000-0001-7463-0580
Jorge Ayón-AguilarHealth Research Medical Coordinator, Mexican Social Security Institute, Puebla Delegation, Puebla, Mexico.ORCID http://orcid.org/0000-0001-9704-8032
Francisco Arellano-AvendañoDepartment of Rheumatology, Medicine School, Meritorious Autonomous University of Puebla, Puebla, Mexico.ORCID http://orcid.org/0009-0000-2189-8524
Álvaro Joaquín Montel-JarquínSpecialties Hospital, Centro Médico Nacional "Manuel Ávila Camacho", IMSS, Puebla, Mexico.ORCID http://orcid.org/0000-0003-0531-9611
Mario García-CarrascoDepartment of Rheumatology, Medicine School, Meritorious Autonomous University of Puebla, Puebla, Mexico.ORCID http://orcid.org/0000-0003-1696-9871
Mexican Social Security Institute · MXBenemérita Universidad Autónoma de Puebla · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Systemic Lupus International Clinics (SLICC)-Frailty Index (FI) is associated with adverse outcomes in systemic lupus erythematosus (SLE). However, to our knowledge, its association with bone mineral density (BMD) and vertebral fractures (VF), has not been investigated using a standardized methods. Our aim was to evaluate the relationship between frailty assessed by SLICC-FI, and BMD and VF in Mestizo women with SLE. Adult women were included in this cross-sectional study. Information concerning the risk factors for VF and BMD in the lumbar spine and total hip was acquired. SLICC-FI was assessed at baseline. A semi-quantitative method was utilized to evaluate the prevalence of VF on lateral thoracolumbar radiographs. Univariate and multivariate regression analyses were performed adjusting for age, body mass index (BMI), SLE duration, cumulative glucocorticoid dose, bisphosphonate use, and BMD measurements. We included 202 women with SLE (mean age [SD] = 43.3 [13.6] years). The mean (SD) SLICC-FI value was 0.14 (0.09). Eleven (5.4%) patients were categorized as robust, 62 (30.7%) as relatively less fit, 84 (41.6%) as least fit, and 45 (22.3%) as frail. Both univariate and multivariate models showed associations between frailty (defined as SLICC-FI > 0.21) and prevalent VF in the entire population (OR 5.76, 95% CI 2.53-13.12; P < 0.001) and in the premenopausal group (OR 4.29, 95% CI; P = 0.047). We also found an association between the SLICC-FI and low BMD. In conclusion, frailty assessed by SLICC-FI might be associated with VF and low BMD in mestizo females with SLE.

Indexed as

Bone Diseases, MetabolicFrailtyLupus Erythematosus, SystemicSpinal FracturesAdolescentAdultBone DensityCross-Sectional StudiesFemaleHumansLumbar VertebraeRisk FactorsFrailtySystemic lupus erythematosusVertebral fractures

Identifiers

PMID37481761
PMCPMC10618373
OpenAlexW4385174067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.