Evidence map›Paper›PMID 37480397›Full record

ArticleInternational journal of bipolar disorders2023

The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder.

Craig Steel, Kim Wright, Guy M Goodwin, Judit Simon, Nicola Morant, Rod S Taylor, Michael Brown, Susie Jennings, Susie A Hales, Jemma Regan and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of bipolar disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 3 countries.

Craig SteelOxford Health NHS Foundation Trust and University of Oxford, Oxford, UK.
Kim WrightUniversity of Exeter, Exeter, EX4 4PY, UK. K.A.Wright@exeter.ac.uk.
Guy M GoodwinUniversity of Oxford, Oxford, UK.
Judit SimonDepartment of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria.
Nicola MorantUniversity College London, London, UK.
Rod S TaylorMRC/CSO Social and Public Health Sciences Unit and Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK.
Michael BrownUniversity of Cambridge, Cambridge, UK.
Susie JenningsUniversity of Reading, Reading, UK.
Susie A HalesOxford Health NHS Foundation Trust and University of Oxford, Oxford, UK.
Jemma ReganDevon Partnership NHS Trust, Devon, UK.
Michaela SibseyUniversity of Reading, Reading, UK.
Zoe ThomasUniversity of Surrey, Surrey, UK.
Lynette MeredithUniversity of East London, London, UK.
Emily A HolmesDepartment of Psychology, Uppsala University, Uppsala, Sweden.
University of Oxford · GBUniversity of Reading · GBDevon Partnership NHS Trust · GBMedical University of Vienna · ATMRC/CSO Social and Public Health Sciences Unit · GBUniversity College London · GBUniversity of Cambridge · GBUniversity of East London · GBUniversity of Exeter · GBUniversity of Surrey · GBUppsala University · SE

Funding

Research for Patient Benefit Programme PB-PG-1216-20009
6 · The paper itself

Abstract

backgroundIntrusive mental imagery is associated with anxiety and mood instability within bipolar disorder and therefore represents a novel treatment target. Imagery Based Emotion Regulation (IBER) is a brief structured psychological intervention developed to enable people to use the skills required to regulate the emotional impact of these images.

methodsParticipants aged 18 and over with a diagnosis of bipolar disorder and at least a mild level of anxiety were randomly assigned (1:1) to receive IBER plus treatment as usual (IBER + TAU) or treatment as usual alone (TAU). IBER was delivered in up to 12 sessions overs 16 weeks. Clinical and health economic data were collected at baseline, end of treatment and 16-weeks follow-up. Objectives were to inform the recruitment process, timeline and sample size estimate for a definitive trial and to refine trial procedures. We also explored the impact on participant outcomes of anxiety, depression, mania, and mood stability at 16-weeks and 32-weeks follow-up.

resultsFifty-seven (28: IBER + TAU, 27: TAU) participants from two sites were randomised, with 50 being recruited within the first 12 months. Forty-seven (82%) participants provided outcome data at 16 and 32-weeks follow-up. Thirty-five participants engaged in daily mood monitoring at the 32-week follow-up stage. Retention in IBER treatment was high with 27 (96%) attending ≥ 7 sessions. No study participants experienced a serious adverse event. DISCUSSION: The feasibility criteria of recruitment, outcome completion, and intervention retention were broadly achieved, indicating that imagery-focused interventions for bipolar disorder are worthy of further investigation.

Indexed as

AnxietyBipolar disorderEmotion regulationFeasibilityMental imageryPsychological intervention

Identifiers

PMID37480397
PMCPMC10363092
OpenAlexW4385073760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.