Evidence map›Paper›PMID 37480329›Full record

ArticleACS sensors2023

Genetically Encoded Boronolectin as a Specific Red Fluorescent UDP-GlcNAc Biosensor.

Jing Zhang, Zefan Li, Yu Pang, Yichong Fan, Hui-Wang Ai

Abstract read
In one paragraph

Article in ACS sensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jing ZhangDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, 1340 Jefferson Park Ave, Charlottesville, Virginia 22908, United States.
Zefan LiDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, 1340 Jefferson Park Ave, Charlottesville, Virginia 22908, United States.ORCID 0000-0003-3019-155X
Yu PangCenter for Membrane and Cell Physiology, University of Virginia School of Medicine, Charlottesville, Virginia 22908, United States.
Yichong FanDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, 1340 Jefferson Park Ave, Charlottesville, Virginia 22908, United States.
Hui-Wang AiDepartment of Molecular Physiology and Biological Physics, University of Virginia School of Medicine, 1340 Jefferson Park Ave, Charlottesville, Virginia 22908, United States.ORCID 0000-0002-5664-3270

Funding

An Integrated Fluorescent Biosensor, Imaging, and Analysis Toolkit for Islet BiologicsR01DK122253 · NIDDK · UNIVERSITY OF VIRGINIA · PI AI, HUIWANG · 2020 to 2023
$1.6M
BapaFPs: Genetically encoded fluorescent indicators to image live-cell nucleotide sugarsU01CA230817 · NCI · UNIVERSITY OF VIRGINIA · PI AI, HUIWANG · 2018 to 2020
$1.4M
NCI NIH HHS U01 CA230817NIDDK NIH HHS R01 DK122253
6 · The paper itself

Abstract

There is great interest in developing boronolectins that are synthetic lectin mimics containing a boronic acid functional group for reversible recognition of diol-containing molecules, such as glycans and ribonucleotides. However, it remains a significant challenge to gain specificity. Here, we present a genetically encoded boronolectin which is a hybrid protein consisting of a noncanonical amino acid (ncAA)

Indexed as

MonosaccharidesUridine DiphosphateAnimalsBoron CompoundsBoronic AcidsGolgi ApparatusMammalsBoron CompoundsBoronic AcidsboronolectinMonosaccharidesUridine Diphosphateboronolectindiol-containing moleculesglycobiologylectin mimicsred fluorescent UDP-GlcNAc biosensor

Identifiers

PMID37480329
PMCPMC10663054

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.