ArticleJournal of translational medicine2023
Dietary flavonoids intake contributes to delay biological aging process: analysis from NHANES dataset.
Article in Journal of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Environmental endocrine disruptors and endometrial cancer: a systematic review of epidemiological studies.Frontiers in endocrinology · 2026Pooled it
- Flavonoid intake and telomere length attrition among middle-aged women: a cross-sectional analysis of the Nurses' Health Study.GeroScience · 2026Article
- Flavonoid-rich dietary patterns and the risk of incident hearing loss: evidence from the UK Biobank cohort.The journal of nutrition, health & aging · 2026Article
- Wild blueberry-derived polyphenol metabolites attenuate telomere shortening in an in vitro model of metabolic syndrome.European journal of nutrition · 2026Article
- Liver Aging Index: A Noninvasive Score for Liver Biological Aging and Liver-Related Outcomes in Multicohorts.Aging cell · 2026Article
- Leveraging large language models for gastrointestinal injury detection in athletes: a medical image analysis approach.Scientific reports · 2026Article
- The association of time-restricted eating and indices of organ-specific aging in relation to metabolic health and obesity.NPJ science of food · 2026Article
- Urinary phytoestrogen metabolites are associated with a reduced risk of hyperuricemia.Clinical rheumatology · 2026Article
- Association Between Asthma and the Risk of Type 2 Diabetes Mellitus: Results From NHANES 2009-2016 Data.International journal of endocrinology · 2026Article
- Article
- Liu Jun Zi Decoction extends lifespan and healthspan through p16/p21 signaling in Caenorhabditis elegans.Biogerontology · 2025Article
- Association of the dietary inflammatory index with multi-organ biological age acceleration.Journal of health, population, and nutrition · 2025Article
- Predictive role of the muscle quality index for testosterone deficiency in adult males based on interpretable machine learning methods.BMC public health · 2025Article
- Flavonol Technology: From the Compounds' Chemistry to Clinical Research.Molecules (Basel, Switzerland) · 2025Review
- Association between dietary flavonoids intake and metabolic dysfunction-associated steatotic liver disease especially in non-smokers: a cross-sectional study in US adults.BMC gastroenterology · 2025Article
- Dietary Quercetin Intake Is Associated With a Lower Risk of Diabetic Nephropathy in US Adults: Data From NHANES 2007-2008, 2009-2010, and 2017-2018.Food science & nutrition · 2025Article
- Association between dietary (poly)phenol intake and the ATHLOS Healthy Ageing Scale in the Polish arm of the HAPIEE study.GeroScience · 2025Article
- Associations between flavonoid-rich food and flavonoid intakes and incident unhealthy aging outcomes in older United States males and females.The American journal of clinical nutrition · 2025Article
- Naringenin Inhibits Colorectal Cancer associated with a High-Fat Diet through Modulation of Gut Microbiota and IL-6/STAT3 Pathway.Journal of microbiology and biotechnology · 2025Article
- The association between dietary quality and biological aging: two-mediation analysis.Aging clinical and experimental research · 2025Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiet may influence biological aging and the discrepancy (∆age) between a subject's biological age (BA) and chronological age (CA). We aimed to investigate the correlation of dietary flavonoids with the ∆age of organs (heart, kidney, liver) and the whole body.
methodA total of 3193 United States adults were extracted from the National Health and Nutrition Examination Survey (NHANES) in 2007-2008 and 2017-2018. Dietary flavonoids intake was assessed using 24-h dietary recall method. Multiple linear regression analysis was performed to evaluate the association of dietary flavonoids intake with the ∆age of organs (heart, kidney, liver) and the whole body. BA was computed based on circulating biomarkers, and the resulting ∆age was tested as an outcome in linear regression analysis.
resultsThe ∆age of the whole body, heart, and liver was inversely associated with higher flavonoids intake (the whole body ∆age β = - 0.58, cardiovascular ∆age β = - 0.96, liver ∆age β = - 3.19) after adjustment for variables. However, higher flavonoids intake positively related to renal ∆age (β = 0.40) in participants with chronic kidney disease (CKD). Associations were influenced by population characteristics, such as age, health behavior, or chronic diseases. Anthocyanidins, isoflavones and flavones had the strongest inverse associations between the whole body ∆age and cardiovascular ∆age among all the flavonoids subclasses.
conclusionFlavonoids intake positively contributes to delaying the biological aging process, especially in the heart, and liver organ, which may be beneficial for reducing the long-term risk of cardiovascular or liver disease.
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