Evidence map›Paper›PMID 37480047›Full record

ArticleItalian journal of pediatrics2023

Preschool-located influenza vaccination and influenza-like illness surveillance: an Italian pilot experience.

Antonella Amendola, Elisa Borghi, Silvia Bianchi, Maria Gori, Clara Fappani, Lucia Barcellini, Federica Forlanini, Nicolò Garancini, Chiara Nava, Alessandra Mari and 7 more

Open access · goldAbstract read
In one paragraph

Article in Italian journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Antonella AmendolaDepartment of Health Sciences, Università degli Studi di Milano, Milan, 20142, Italy. antonella.amendola@unimi.it.ORCID http://orcid.org/0000-0002-0499-8977
Elisa BorghiDepartment of Health Sciences, Università degli Studi di Milano, Milan, 20142, Italy.
Silvia BianchiDepartment of Health Sciences, Università degli Studi di Milano, Milan, 20142, Italy.
Maria GoriDepartment of Health Sciences, Università degli Studi di Milano, Milan, 20142, Italy.
Clara FappaniDepartment of Health Sciences, Università degli Studi di Milano, Milan, 20142, Italy.
Lucia BarcelliniDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, 20154, Italy.
Federica ForlaniniDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, 20154, Italy.
Nicolò GaranciniDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, 20154, Italy.
Chiara NavaDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, 20154, Italy.
Alessandra MariDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, 20154, Italy.
Anna SalaDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, 20154, Italy.
Chiara GaspariniDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, 20154, Italy.
Emerenziana OttavianoDepartment of Health Sciences, Università degli Studi di Milano, Milan, 20142, Italy.
Daniela ColzaniDepartment of Health Sciences, Università degli Studi di Milano, Milan, 20142, Italy.
Elia Mario BiganzoliDepartment of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milan, 20157, Italy.
Elisabetta TanziDepartment of Health Sciences, Università degli Studi di Milano, Milan, 20142, Italy.
Gian Vincenzo ZuccottiDepartment of Pediatrics, V. Buzzi Children's Hospital, Università degli Studi di Milano, Milan, 20154, Italy.
University of Milan · IT

Funding

AstraZeneca ESR-21-21427
6 · The paper itself

Abstract

backgroundWe describe the first school-located influenza vaccination campaign with quadrivalent live-attenuated influenza vaccine (LAIV) among pre-school children in Italy, coupled with an innovative school-centred influenza-like illnesses (ILIs) surveillance using a self-sampling non-invasive saliva collection method.

methodsThe pilot study was proposed during the 2021/2022 influenza season to fifteen pre-schools in the Milan municipality. LAIV was offered directly in school to all healthy children without contraindications. ILI differential diagnosis was conducted by real-time RT-PCR for influenza A/B and SARS-CoV-2.

resultsFive pre-schools were involved in the pilot project and overall, 135 families (31.2%) participated in the study, adhering to both surveillance and vaccination; 59% of families had an immigrant background. No pupil experienced adverse reactions after vaccination. Nineteen saliva samples were collected from sixteen children (11.8%). Six samples (31.6%) tested positive for SARS-CoV-2; none was positive for influenza A/B.

conclusionsThe participation in the immunisation campaign was good, considering possible absences due to COVID-19 pandemic, and the intranasal administration was well tolerated and helped to overcome parental hesitancy. Saliva sampling represented a useful tool to reduce children's stress and increase parents' compliance. The high participation of families with an immigrant background suggests that school-based interventions can represent an effective strategy to overcome socioeconomic and cultural barriers.

Indexed as

COVID-19Influenza, HumanVirus DiseasesChildChild, PreschoolHumansItalyPandemicsPilot ProjectsSARS-CoV-2VaccinationChildrenHealth equityLive-attenuated influenza vaccinationSalivaSchool-located vaccinationSelf-sampling

Identifiers

PMID37480047
PMCPMC10362647
OpenAlexW4385064283

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.