ArticleBMC cardiovascular disorders2023
One-step integrated coronary-carotid-cerebral computed tomography angiography to evaluate cardiovascular and cerebrovascular atherosclerosis.
Article in BMC cardiovascular disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Impact of arm position on low dose dual-source CT one-step aortic and cerebral-carotid artery angiography image quality and radiation dose.BMC medical imaging · 2025Trial
- Serum GPX4, ALOX15, and FPN1 are associated with severity of carotid atherosclerosis: a cross-sectional observational study.BMC neurology · 2026Observational
- A wide-detector CT protocol for one-stop cardio-cerebrovascular angiography: a technical feasibility study comparing an integrated protocol with conventional two-scan approach.Frontiers in radiology · 2026Article
- Incremental value of coronary computed tomography-derived fractional flow reserve for the prediction of major adverse cardiovascular events in patients with ischemic stroke.Quantitative imaging in medicine and surgery · 2025Article
- Low KV-low contrast medium dose one-stop dual source CT high pitch integrated coronary-carotid-cerebral-aortic CTA improves image quality and reduces both radiation and contrast medium doses.European journal of radiology open · 2025Article
- Comparison of "one-stop" coronary and head-and-neck computed tomography angiography with different scan sequences using a wide-detector system: heart-to-cranialQuantitative imaging in medicine and surgery · 2025Article
- Predicting asymptomatic coronary artery disease in first-ever acute ischemic stroke patients: a cross-sectional study.Quantitative imaging in medicine and surgery · 2024Article
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Authors and funding
7 authors.
Funding
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Abstract
purposeThis study aims to develop a low-radiation dose, one-step integrated coronary-carotid-cerebral computed tomography angiography (ICCC-CTA) technique to analyze the relationship between cardiovascular and cerebrovascular atherosclerosis and evaluate the risk factors of plaque to provide an early-stage treatment to patients and reduce vascular events.
methodsA total of 300 consecutive asymptomatic patients with cardiovascular risk factors who underwent ICCC-CTA were enrolled in this prospective study. The association between coronary and carotid-cerebrovascular atherosclerosis was assessed. The primary cardiovascular risk factors for various plaque types in cardiovascular or cerebrovascular disease were evaluated using multivariate analysis.
resultsAmong 300 patients, 189 (63%) had plaques in their coronary and cerebral arteries. The presence of calcified and mixed plaques in the carotid-cerebral and coronary arteries was strongly correlated (χ
conclusionsWe confirm that elevated blood glucose and total cholesterol levels are associated with coronary and carotid-cerebrovascular plaques using the novel one-step low dose cerebral-carotid-cardiac CTA technique. These findings will provide insights for further studies focusing on developing low-radiation dose one-step ICCC-CTA to screen cardiovascular/cerebrovascular plaques in general population with cardiovascular risk factors. ADVANCES IN KNOWLEDGE: We developed a low-radiation dose, one-step ICCC-CTA technique to detect cardiovascular and cerebrovascular atherosclerosis. We evaluated the risk factors for plaque burden for the early treatment and reduction of vascular events. These findings supported the development of low-radiation dose one-step ICCC-CTA to screen for cardiovascular/cerebrovascular disease in general population with cardiovascular risk factors.
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