Evidence map›Paper›PMID 37479957›Full record

ArticleRheumatology and therapy2023

Is the Rate of Responders to Hyaluronic Acid Injection for Patients with Knee Osteoarthritis Stable Over Time? Post hoc Analyses of a 6-Month Follow-Up Study.

Olivier Bruyere, Germain Honvo, Eduard Vidovic, Bernard Cortet

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Rheumatology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Olivier BruyereWHO Collaborating Centre for Epidemiology of Musculo-Skeletal Health and Ageing, Research Unit in Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium. olivier.bruyere@uliege.be.ORCID http://orcid.org/0000-0003-4269-9393
Germain HonvoWHO Collaborating Centre for Epidemiology of Musculo-Skeletal Health and Ageing, Research Unit in Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium.
Eduard VidovicAptissen SA Medical Department, Plan-les-Ouates, Switzerland.
Bernard CortetDepartment of Rheumatology and UR 4490, University Hospital of Lille, Lille, France.
University of Liège · BELille’s Cardiology Hospital · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRecently, a study showing the non-inferiority of a single injection of sodium hyaluronate plus sorbitol (Synolis VA

methodsResponders to treatment at days 28, 84, and 168 were evaluated according to the responder criteria proposed by the OMERACT-OARSI. The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used to assess functional status at baseline. All analyses were adjusted for age, gender, BMI, and baseline WOMAC total score using data from the intention-to-treat (ITT) population.

resultsOut of the 96 patients included in the study who were receiving Synolis VA

conclusionsAn early response of a single injection of sodium hyaluronate plus sorbitol is predictive of long-term response, up to 24 weeks. Patients with a poorer physical function may best benefit from the treatment.

Indexed as

Hyaluronic acidKnee osteoarthritisPost hoc analysisResponders

Identifiers

PMID37479957
PMCPMC10469129
OpenAlexW4385064820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.