Evidence map›Paper›PMID 37479746›Full record

ArticlePediatric research2023

Maternal stress and early childhood BMI among US children from the Environmental influences on Child Health Outcomes (ECHO) program.

Charles T Wood, Marie L Churchill, Monica McGrath, Judy Aschner, Steven M Brunwasser, Sarah Geiger, Semsa Gogcu, Tina V Hartert, Allison E Hipwell, Kathleen Lee-Sarwar and 11 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03061890 (Developmental Impact of Neonatal Intensive Care Unit), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03061890 completednot on this map

Developmental Impact of Neonatal Intensive Care Unit (NICU) Exposures: Environmental Influences on Child Health Outcomes (ECHO)

Typeobservational_patient_registrySponsorAlbert Einstein College of MedicineRan2017 to 2023Enrolled600ConditionsPrematurity
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 20 institutions in 2 countries.

Charles T WoodDivision of General Pediatrics and Adolescent Health and Duke Center for Childhood Obesity Research, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA. charles.wood@duke.edu.ORCID 0000-0002-6884-8265
Marie L ChurchillDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Monica McGrathDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Judy AschnerDepartment of Pediatrics, Hackensack Meridian School of Medicine, Nutley, NJ, USA.
Steven M BrunwasserDepartment of Psychology, Rowan University, Glassboro, NJ, USA.
Sarah GeigerDepartment of Kinesiology and Community Health, and Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Champaign, IL, USA.
Semsa GogcuDivision of Neonatology, Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Tina V HartertDepartments of Medicine and Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Allison E HipwellDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Kathleen Lee-SarwarDepartment of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Kristen LyallAJ Drexel Autism Institute, Drexel University, Philadelphia, PA, USA.
Nora K MoogDepartment of Medical Psychology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.
Thomas G O'ConnorDepartment of Psychiatry, Psychology, Neuroscience, and Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, NY, USA.
T Michael O'SheaDivision of Neonatal-Perinatal Medicine, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
P Brian SmithDivision of Neonatology, Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Rosalind J WrightEnvironmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Xueying ZhangEnvironmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Emily ZimmermanDepartment of Communication Sciences and Disorders, Northeastern University, Boston, MA, USA.
Kathi C HuddlestonCollege of Public Health, George Mason University, Fairfax, VA, USA.
Callie L BrownDivision of General Pediatrics, Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
program collaborators for Environmental influences on Child Health Outcomes
Boston Medical Center · USNorthwestern University · USBoston University · USBrigham and Women's Hospital · USIcahn School of Medicine at Mount Sinai · USJohns Hopkins University · USNortheastern University · USUniversity of Illinois Urbana-Champaign · USBoston Children's Hospital · USClinical Research Institute · USDuke University · USUniversity of Wisconsin–Madison · USWake Forest University · USAlbert Einstein College of Medicine · USDrexel University · USGeorge Mason University · USHumboldt-Universität zu Berlin · DEMagee-Womens Hospital · USRowan University · USRTI International · US

Funding

Project-005U2COD023375 · OD · DUKE UNIVERSITY · PI Linda S Adair, Phillip Brian Smith · 2016 to 2026
$215.9M
ECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4M
Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUH3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI James E. Gern · 2018 to 2026
$64.8M
Mount Sinai ECHO site for Perinatal Environment and Development StudiesUH3OD023337 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KECIA Nicole CARROLL, Robert O Wright · 2018 to 2026
$54.1M
Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
The ECHO Measurement Core: A Framework and Resource for Assessing Environmental Exposure and Child HealthU24OD023319 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Courtney K Blackwell, RICHARD GERSHON · 2016 to 2026
$43.7M
VISUAL INDICES OF NEUROTOXICITYP30ES001247 · NIEHS · UNIVERSITY OF ROCHESTER · PI Martha Susiarjo · 1985 to 2026
$42.8M
Environmental Influences on Child Health Outcomes in Puerto Rico (ECHO-PRO)UH3OD023251 · OD · NORTHEASTERN UNIVERSITY · PI Akram N Alshawabkeh · 2018 to 2026
$24.0M
The Developing Brain: Influences and OutcomesUH3OD023313 · OD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI Viren Andrew D'Sa, Daphne Koinis Mitchell · 2018 to 2026
$20.7M
Wisconsin Infant Study Cohort (WISC) ECHO Pediatric Follow-UpUG3OD023282 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI GERN, JAMES E. · 2016 to 2024
$19.3M
The Illinois Kids Development Study ECHO Pregnancy and Pediatric CohortUH3OD023272 · OD · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Andrea Aguiar, Susan L Schantz · 2018 to 2026
$18.6M
Pre- and Postnatal Exposure Periods for Child Health: Common Risks and Shared MechanismsUH3OD023349 · OD · UNIVERSITY OF ROCHESTER · PI Emily S Barrett, Richard Kermit Miller · 2018 to 2026
$15.9M
NCATS NIH HHS UL1 TR004419NIEHS NIH HHS P30 ES001247NIH HHS U24 OD023319NIH HHS U24 OD023382NIH HHS U2C OD023375NIH HHS UG3 OD023244NIH HHS UG3 OD023272NIH HHS UG3 OD023282NIH HHS UG3 OD023320NIH HHS UG3 OD023342NIH HHS UG3 OD035513NIH HHS UG3 OD035516NIH HHS UG3 OD035517NIH HHS UG3 OD035521NIH HHS UG3 OD035546NIH HHS UH3 OD023244NIH HHS UH3 OD023251NIH HHS UH3 OD023268NIH HHS UH3 OD023272NIH HHS UH3 OD023282NIH HHS UH3 OD023313NIH HHS UH3 OD023320NIH HHS UH3 OD023337NIH HHS UH3 OD023342NIH HHS UH3 OD023349NIH HHS UH3 OD035513NIH HHS UH3 OD035521NIH HHS UH3 OD035532
6 · The paper itself

Abstract

backgroundWe aimed to understand the association between maternal stress in the first year of life and childhood body mass index (BMI) from 2 to 4 years of age in a large, prospective United States-based consortium of cohorts.

methodsWe used data from the Environmental influences on Child Health Outcomes program. The main exposure was maternal stress in the first year of life measured with the Perceived Stress Scale (PSS). The main outcome was the first childhood BMI percentile after age 2 until age 4 years. We used an adjusted linear mixed effects model to examine associations between BMI and PSS quartile.

resultsThe mean BMI percentile in children was 59.8 (SD 30) measured at 3.0 years (SD 1) on average. In both crude models and models adjusted for maternal BMI, age, race, ethnicity, infant birthweight, and health insurance status, no linear associations were observed between maternal stress and child BMI.

conclusionsAmong 1694 maternal-infant dyads, we found no statistically significant relationships between maternal perceived stress in the first year of life and child BMI after 2 through 4 years. IMPACT: Although existing literature suggests relationships between parental stress and childhood BMI, we found no linear associations between maternal stress in the first year of life and childhood BMI at 2-4 years of age among participants in ECHO cohorts. Higher maternal stress was significantly associated with Hispanic ethnicity, Black race, and public health insurance. Our analysis of a large, nationally representative sample challenges assumptions that maternal stress in the first year of life, as measured by a widely used scale, is associated with offspring BMI.

Indexed as

Outcome Assessment, Health CareBirth WeightBody Mass IndexChildChild, PreschoolHumansInfantProspective StudiesRisk FactorsUnited States

Identifiers

PMID37479746
PMCPMC10938641
OpenAlexW4385064588

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.