Evidence map›Paper›PMID 37479480›Full record

ArticleJournal of neurointerventional surgery2024

Mechanical thrombectomy in medium vessel occlusions using the novel aspiration Q catheters: an international multicenter experience.

Andre Monteiro, Hegoda Levansri Dilrukshan Makalanda, James Wareham, Jesse Jones, Ammad A Baig, Permesh Singh Dhillon, Pervinder Bhogal, Maxim Mokin, Waleed Brinjikji, Adnan H Siddiqui

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of neurointerventional surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 2 countries.

Andre MonteiroNeurosurgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Hegoda Levansri Dilrukshan MakalandaDepartment of Interventional Neuroradiology, Royal London Hospital, London, UK.
James WarehamNorth Bristol NHS Trust, Westbury on Trym, Bristol, UK.
Jesse JonesDepartment of Neurosurgery, The University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID http://orcid.org/0000-0002-2682-9736
Ammad A BaigNeurosurgery, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.ORCID http://orcid.org/0000-0002-8241-6864
Permesh Singh DhillonInterventional Neuroradiology, Queen's Medical Centre Nottingham University Hospital NHS Trust, Nottingham, UK.ORCID http://orcid.org/0000-0003-4353-4515
Pervinder BhogalInterventional Neuroradiology, Royal London Hospital, London, UK.ORCID http://orcid.org/0000-0002-5514-5237
Maxim MokinNeurosurgery, Neurosurgery and Brain Repair, University of South Florida, Tampa, Florida, USA.ORCID http://orcid.org/0000-0003-4270-8667
Waleed BrinjikjiRadiology, Mayo Clinic Minnesota, Rochester, Minnesota, USA.ORCID http://orcid.org/0000-0001-5271-5524
Adnan H SiddiquiNeurosurgery, Gates Vascular Institute, Buffalo, New York, USA asiddiqui@ubns.com.ORCID http://orcid.org/0000-0002-9519-0059
Gates (United States) · USRoyal London Hospital · GBJacobs Institute · USMayo Clinic · USNorth Bristol NHS Trust · GBQueen's Medical Centre · GBUniversity of Alabama at Birmingham · USUniversity of South Florida · US

Funding

Optimizing Approaches to Endovascular Therapy of Acute Ischemic StrokeR21NS109575 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI MOKIN, MAXIM · 2019 to 2019
$420k
NINDS NIH HHS R21 NS109575
6 · The paper itself

Abstract

backgroundMedium vessel occlusions (MeVOs) comprise a large proportion of all stroke events. We performed a multicenter study of MIVI Q catheters, a novel design that optimizes suction forces without an increase in lumen diameter, for the treatment of MeVOs, aiming to evaluate its efficacy and safety.

methodsDatabases of two US and two UK centers were retrospectively reviewed for MeVO patients (M2-M3, anterior cerebral artery (ACA), or posterior cerebral artery (PCA)) treated with Q catheters. Outcomes were assessed as successful recanalization (modified Thrombolysis in Cerebral Infarction (mTICI) score ≥2b), first pass effect (FPE), and modified FPE (mFPE) as single pass achieving mTICI ≥2c and mTICI≥2b, respectively, and 90 day modified Rankin Scale (mRS) score.

results69 patients were included (median age 71 years, IQR 56-82.5; 52.2% men). Median National Institutes of Health Stroke Scale (NIHSS) score at admission was 14, and Alberta Stroke Program Early CT Score (ASPECTS) was 9. Primary (without large vessel occlusion (LVO)) and secondary (with LVO) MeVOs represented 47.8% and 52.2% of cases, respectively. Q catheters used were Q3 (47.8%), Q4 (33.3%), Q5 (10.1%), and Q6 (8.7%). mTICI≥2b was achieved in 92.8% of patients, with FPE in 47.8%, and mFPE in 68.1%. Two (2.9%) intraprocedural complications (symptomatic intracranial hemorrhage) occurred. 50% (27/54) achieved an mRS score of ≤2 at the 90 day follow-up. The median NIHSS at admission was significantly higher in secondary than in primary MeVOs (19.5 vs 12, P=0.009). The rate of mRS ≤2 at 90 days was significantly higher in primary than in secondary MeVOs (77.3% vs 31.3%, P=0.002).

conclusionsTreatment of MeVO patients with Q catheters resulted in optimal angiographic and clinical outcomes. Although angiographic results were similar between primary and secondary MeVOs, the former had less severe presenting NIHSS and better outcomes at 90 days than the latter.

Indexed as

CathetersThrombectomyAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeDeviceStrokeThrombectomy

Identifiers

PMID37479480
PMCPMC11187364
OpenAlexW4385063899

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.