ArticleJMIR human factors2023
An Artificial Therapist (Manage Your Life Online) to Support the Mental Health of Youth: Co-Design and Case Series.
Article in JMIR human factors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Usability and User Experience Assessment of Health Care Conversational Agents Using Validated Subjective Instruments: Systematic Review and Comparative Analysis.JMIR human factors · 2026Pooled it
- A Shift in Trust: An Analysis of the Use of AI Chatbots Among People Living With Bipolar Disorder.Bipolar disorders · 2026Article
- Reimagining psychiatric care with agentic AI: promise, challenges, and a roadmap forward.NPJ digital medicine · 2026Review
- A Rule-Based Conversational Agent for Mental Health and Well-Being in Young People: Formative Case Series During the Rise of Generative AI.JMIR formative research · 2025Article
- Digital Conversational Agents for the Mental Health of Treatment-Seeking Youth: Scoping Review.JMIR mental health · 2025Article
- The Digital Therapeutic Alliance With Mental Health Chatbots: Diary Study and Thematic Analysis.JMIR mental health · 2025Article
- Charting the evolution of artificial intelligence mental health chatbots from rule-based systems to large language models: a systematic review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- The use of co-design with young people for digital mental health support development: A systematic review.Internet interventions · 2025Review
- A Scoping Review of AI-Driven Digital Interventions in Mental Health Care: Mapping Applications Across Screening, Support, Monitoring, Prevention, and Clinical Education.Healthcare (Basel, Switzerland) · 2025Review
- Digital Mental Health Interventions for Young People Aged 16-25 Years: Scoping Review.Journal of medical Internet research · 2025Article
- Current Landscape and Future Directions for Mental Health Conversational Agents for Youth: Scoping Review.JMIR medical informatics · 2025Article
- Persuasive chatbot-based interventions for depression: a list of recommendations for improving reporting standards.Frontiers in psychiatry · 2025Article
- A pilot study of the perceptions and acceptability of guidance using artificial intelligence in internet cognitive behaviour therapy for perfectionism in young people.Internet interventions · 2024Article
- User perceptions and experiences of an AI-driven conversational agent for mental health support.mHealth · 2024Article
- Exploring the Role of Artificial Intelligence in Mental Healthcare: Current Trends and Future Directions - A Narrative Review for a Comprehensive Insight.Risk management and healthcare policy · 2024Review
- Systematic review and meta-analysis of AI-based conversational agents for promoting mental health and well-being.NPJ digital medicine · 2023Review
- Waiting for a digital therapist: three challenges on the path to psychotherapy delivered by artificial intelligence.Frontiers in psychiatry · 2023Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence of child and adolescent mental health issues is increasing faster than the number of services available, leading to a shortfall. Mental health chatbots are a highly scalable method to address this gap. Manage Your Life Online (MYLO) is an artificially intelligent chatbot that emulates the method of levels therapy. Method of levels is a therapy that uses curious questioning to support the sustained awareness and exploration of current problems.
objectiveThis study aimed to assess the feasibility and acceptability of a co-designed interface for MYLO in young people aged 16 to 24 years with mental health problems.
methodsAn iterative co-design phase occurred over 4 months, in which feedback was elicited from a group of young people (n=7) with lived experiences of mental health issues. This resulted in the development of a progressive web application version of MYLO that could be used on mobile phones. We conducted a case series to assess the feasibility and acceptability of MYLO in 13 young people over 2 weeks. During this time, the participants tested MYLO and completed surveys including clinical outcomes and acceptability measures. We then conducted focus groups and interviews and used thematic analysis to obtain feedback on MYLO and identify recommendations for further improvements.
resultsMost participants were positive about their experience of using MYLO and would recommend MYLO to others. The participants enjoyed the simplicity of the interface, found it easy to use, and rated it as acceptable using the System Usability Scale. Inspection of the use data found evidence that MYLO can learn and adapt its questioning in response to user input. We found a large effect size for the decrease in participants' problem-related distress and a medium effect size for the increase in their self-reported tendency to resolve goal conflicts (the proposed mechanism of change) in the testing phase. Some patients also experienced a reliable change in their clinical outcome measures over the 2 weeks.
conclusionsWe established the feasibility and acceptability of MYLO. The initial outcomes suggest that MYLO has the potential to support the mental health of young people and help them resolve their own problems. We aim to establish whether the use of MYLO leads to a meaningful reduction in participants' symptoms of depression and anxiety and whether these are maintained over time by conducting a randomized controlled evaluation trial.
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