Evidence map›Paper›PMID 37477932›Full record

ArticleInvestigative ophthalmology & visual science2023

Corneal Biomechanical Properties Demonstrate Anisotropy and Correlate With Axial Length in Myopic Eyes.

Lingfeng Chen, Yangyi Huang, Xiaoyu Zhang, Yike Shi, Zhipeng Gao, Bingqing Sun, Yang Shen, Ling Sun, Yifan Cao, Qianqian Zhang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Investigative ophthalmology & visual science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Soft, Flexible, and Stretchable Platforms for Tissue-Interfaced Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lingfeng ChenCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi, China.
Yangyi HuangEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Xiaoyu ZhangEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Yike ShiCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi, China.
Zhipeng GaoCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi, China.
Bingqing SunEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Yang ShenEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Ling SunEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Yifan CaoCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi, China.
Qianqian ZhangCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi, China.
Jiqiang GuoShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Fen LiCollege of Mechanical and Vehicle Engineering, Taiyuan University of Technology, Taiyuan, China.
Weiyi ChenCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi, China.
Xiaona LiCollege of Biomedical Engineering, Taiyuan University of Technology, Taiyuan, Shanxi, China.
Xingtao ZhouEye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The purpose of this study was to investigate the ex vivo and in vivo biomechanical characteristic of cornea in myopic eyes. Methods: Fifty-one corneal stromal lenticules were obtained from myopic eyes during the SMILE procedure and were tested by a biaxial tensile system within 24 hours postoperatively. The material properties of the lenticules were described using stress-strain curves and were compared among axial length (AL) <26 mm and AL ≥ 26 mm group. Pre-operative stress-strain index (SSI) parameters were used to evaluate the biomechanical properties of the cornea in vivo. Results: Compared with AL < 26 mm, the tangent modulus significantly decreased in horizontal and vertical directions when AL ≥ 26 mm (P < 0.05); SSI also significantly decreased when AL ≥ 26 mm (P < 0.05). Anisotropic parameter is positively correlated with AL (r = 0.307, P < 0.05). Compared with AL < 26 mm, anisotropic parameter significantly increased when AL ≥ 26 mm (P < 0.05). SSI was negatively correlated with AL (r = -0.380, P < 0.05) in the AL < 26 mm group but not in the AL ≥ 26 mm group (P > 0.05). Compared with 26 mm ≤ AL < 27 mm group, the tangent modulus significantly decreased in the horizontal direction (P < 0.05) but not in the vertical direction when 27 mm ≤ AL < 28 mm (P > 0.05). Conclusions: The biomechanical properties of cornea decreased with the increase of AL. Tangent modulus significantly decreased in the horizontal direction compared with vertical direction. AL should be taken into account during calculation of corneal biomechanical parameters in order to improve validity.

Indexed as

CorneaMyopiaAnisotropyBiomechanical PhenomenaCorneal StromaHumans

Identifiers

PMID37477932
PMCPMC10365135

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.