Evidence map›Paper›PMID 37477790›Full record

ReviewJournal of neurovirology2023

Norovirus-associated neurological manifestations: summarizing the evidence.

Shramana Deb, Ritwick Mondal, Durjoy Lahiri, Gourav Shome, Aakash Guha Roy, Vramanti Sarkar, Shramana Sarkar, Julián Benito-León

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of neurovirology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Clinical and Genotypic Features of Norovirus Enteritis in Children Complicated by Convulsions: A Retrospective Study in Kunming, China.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Shramana DebDepartment of Neuroscience, S.N. Pradhan Centre for Neuroscience, Kolkata, India.ORCID 0000-0003-3383-4063
Ritwick MondalDepartment of Clinical Pharmacology and Therapeutic Medicine, IPGMER and SSKM Hospital, Kolkata, India.ORCID 0000-0002-4288-7661
Durjoy LahiriDepartment of Cognitive Neurology, Baycrest Health Sciences and Rotman Research Institute, University of Toronto, Ontario, Canada.ORCID 0000-0002-2487-9537
Gourav ShomeDivision of Molecular Medicine, Bose Institute, Kolkata, India.ORCID 0000-0003-1186-5029
Aakash Guha RoyDepartment of Internal Medicine, SSKM and IPGMER Hospital, Kolkata, India.
Vramanti SarkarDepartment of Neuroscience, S.N. Pradhan Centre for Neuroscience, Kolkata, India.
Shramana SarkarDepartment of Internal Medicine, SSKM and IPGMER Hospital, Kolkata, India.
Julián Benito-LeónDepartment of Neurology, University Hospital "12 de Octubre", Madrid, Spain. jbenitol67@gmail.com.ORCID 0000-0002-1769-4809
Institute of Post Graduate Medical Education and Research · INInstitute of Neurosciences Kolkata · INBose Institute · INUniversidad Complutense de Madrid · ESUniversity of Toronto · CA

Funding

ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMORR01NS039422 · NINDS · YALE UNIVERSITY · PI LOUIS, ELAN D · 2000 to 2013
$7.7M
NINDS NIH HHS R01 NS039422
6 · The paper itself

Abstract

Norovirus, a positive-stranded RNA virus, is one of the leading causes of acute gastroenteritis among all age groups worldwide. The neurological manifestations of norovirus are underrecognized, but several wide-spectrum neurological manifestations have been reported among infected individuals in the last few years. Our objective was to summarize the features of norovirus-associated neurological disorders based on the available literature. We used the existing PRISMA consensus statement. Data were collected from PubMed, EMBASE, Web of Science, and Scopus databases up to Jan 30, 2023, using pre-specified searching strategies. Twenty-one articles were selected for the qualitative synthesis. Among these, seven hundred and seventy-four patients with norovirus-associated neurological manifestations were reported. Most cases were seizure episodes, infection-induced encephalopathy, and immune-driven disorders. However, only a few studies have addressed the pathogenesis of norovirus-related neurological complications. The pathogenesis of these manifestations may be mediated by either neurotropism or aberrant immune-mediated injury, or both, depending on the affected system. Our review could help clinicians to recognize these neurological manifestations better and earlier while deepening the understanding of the pathogenesis of this viral infection.

Indexed as

Brain DiseasesCaliciviridae InfectionsGastroenteritisNorovirusHumansSeizuresClinical manifestationsNorovirusNorovirus-associated neurological disordersSeizures

Identifiers

PMID37477790
PMCPMC10501950
OpenAlexW4384922717

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.