ArticleEndocrine2023
Comparison of plasma oxytocin level in women with natural and surgical menopause.
Article in Endocrine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- Oxytocin and women's health in midlife.The Journal of endocrinology · 2024Review
- The Role of Oxytocin in Polycystic Ovary Syndrome: A Systematic Review.Current issues in molecular biology · 2024Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to investigate plasma oxytocin level in women with natural and surgical menopause and its relation with other metabolic parameters.
methodsThis study included 89 postmenopausal women admitted to menopausal outpatient clinics and gave written consent to participate. Participants were allocated into natural (Group 1; n = 61) and surgical (Group 2; n = 28) menopause groups based on causative process for the onset of menopause. After the clinical evaluation and physical examination, blood samples are collected for biochemical profile and plasma oxytocin levels. The complete blood count, lipid profile, thyroid panel, blood glucose concentration, vitamin D and liver enzymes were measured by autoanalyzer, plasma oxytocin level was measured spectrophotometrically by ELISA method.
resultsThe groups were comparable for age, body mass index, menopause duration, gravity and blood parameters measured except significantly different plasma oxytocin levels between the two groups as 6.8 (3.2-20.6) ng/ml in natural menopause group and 4.2 (2.9-18.2) ng/ml in surgical menopause group (p < 0.001). Plasma oxytocin level was also negatively correlated with age (r = -0.245, p = 0.022) and menopausal duration (r = -0.275, p = 0.01).
conclusionOur results point out that oxytocin might be a target hormone to manage menopause associated disorders and/or it should be considered for its role in the differences in the incidences of postmenopausal diseases and quality of life in the course of natural and surgical menopausal transition.
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Registered trials
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