Evidence map›Paper›PMID 37477683›Full record

Observational studyWorld journal of urology2023

Impact of robotic-assisted kidney transplantation on post-transplant infections: a case-control study.

Sabina Herrera, Irene Carbonell, Frederic Cofan, David Cucchiari, Iolanda Abalde, Emilia Bernabeu, Abiu Sempere, Lluís Peri, Ignacio Revuelta, Fritz Diekmann and 3 more

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Sabina HerreraHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.ORCID http://orcid.org/0000-0002-5057-354X
Irene CarbonellHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
Frederic CofanHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
David CucchiariHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
Iolanda AbaldeHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
Emilia BernabeuHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
Abiu SempereHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
Lluís PeriHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
Ignacio RevueltaHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
Fritz DiekmannHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
Antonio AlcarazHospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain.
Mireia Musquera *Hospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain. mmusquer@clinic.cat.
Marta Bodro *Hospital Clinic de Barcelona, C. de Villarroel, 170, 08036, Barcelona, Spain. mbodro@clinic.cat.
Hospital Clínic de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to determine the differences in the incidence, epidemiology, clinical characteristics and risk factors of infections in living donor kidney transplant recipients using robotic-assisted kidney transplantation (RAKT) and open approach.

methodsWe conducted a retrospective observational study from January 2016 to December 2019. For the risk factor analysis, a matched case-control study (1:1 ratio) was performed (robotic vs open). Control subjects were matched for living donor and time of transplantation. The data included de novo immunosuppressive regimen, delayed graft function, urological complications, acute allograft rejection and incidence, clinical features, microbiological findings and outcomes of infections.

resultsNinety-four RAKT and 84 controls were included. There were no differences between groups in terms of age, gender, BMI, median days of hospitalization, immunosuppressive regimen, need for surgical urologic procedures post-transplantation, presence of urinary leak or acute allograft rejection. Thirty-five percent of all recipients analyzed presented an infection, mostly asymptomatic bacteriuria (49%), symptomatic urinary tract infection (31%) and surgical site infection (10%). Pseudomonas aeruginosa was the most frequent isolated microorganism in 67%, followed by E. coli (20%), Enterococcus faecalis (17%) and Klebsiella pneumoniae (10%). Eight percent of the microorganisms were multidrug resistant. The open kidney transplantation group presented more infections compared to RAKT (43 vs 27%, p = 0.04). After multivariate analysis, need for surgical urologic procedure post-transplantation (OR 6.2, 95% CI 1.1-35), BMI ≥ 30 (OR 3.6, 95% CI 1.5-9) and acute allograft rejection (OR 3.2, 95% CI 1.2-8.5) were associated with infection, whereas RAKT (OR 0.5, 95% CI 0.2-0.9) and the use of JJ catheter (OR 0.36, 95% CI 0.17-0.72) were protective factors.

conclusionsInfection is a frequent event in patients receiving a living donor kidney transplant. Acute allograft rejection, need for surgical urologic procedure post-transplantation and BMI were associated with infection, whereas robotic surgery was a protective factor in living donor kidney transplantation.

Indexed as

Kidney TransplantationRobotic Surgical ProceduresCase-Control StudiesEscherichia coliHumansKidneyGram-negative bacilliInfectionPseudomonas aeruginosaRoboticTransplant

Identifiers

PMID37477683
OpenAlexW4384924786

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.