Evidence map›Paper›PMID 37477680›Full record

ArticleArchives of dermatological research2023

Association between Hashimoto's thyroiditis and melanoma: a retrospective matched cohort study.

B G Gorman, E Campbell, B L Mullen, N Deo, J Ahn, S Carley, M R Castro, A Todd, N Y Vidal

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of dermatological research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

B G GormanMayo Clinic Alix School of Medicine, 200 First Street SW, Rochester, MN, 55905, USA. gorman.benjamin@mayo.edu.
E CampbellDepartment of Dermatology, Mayo Clinic, Rochester, MN, USA.
B L MullenMayo Clinic Alix School of Medicine, 200 First Street SW, Rochester, MN, 55905, USA.
N DeoMayo Clinic Alix School of Medicine, 200 First Street SW, Rochester, MN, 55905, USA.
J AhnDepartment of Dermatology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
S CarleySharp Rees-Stealy Dermatology, San Diego, CA, USA.
M R CastroDivision of Endocrinology, Mayo Clinic, Rochester, MN, USA.
A ToddClinical Trials and Biostatistics Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
N Y VidalDepartment of Dermatology, Mayo Clinic, Rochester, MN, USA.
WinnMed · USMayo Clinic · USMayo Clinic in Arizona · USSharp Rees-Stealy Medical Group · USUniversity of Pittsburgh Medical Center · US

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002377
6 · The paper itself

Abstract

An inflammatory microenvironment has been shown to increase risk for malignant melanoma, suggesting that melanoma may be related to a pro-inflammatory state. Though Hashimoto's thyroiditis is one of the most common autoimmune diseases, there are no investigations of its relationship with melanoma. We aim to determine if Hashimoto's increases risk of developing melanoma. A retrospective, validated cohort of patients with a diagnosis of Hashimoto's between 2005 and 2020 were identified using the Olmsted County database. Patients were age and sex matched to controls without a Hashimoto's diagnosis. The primary outcomes were development of melanoma and time to first melanoma diagnosis. 4805 patients were included in the study, with 1726 (36%) having a diagnosis of Hashimoto's. Hashimoto's patients had no significant difference in risk of melanoma (relative risk 0.96, 95% CI 0.78-1.17) or nonmelanoma skin cancer (relative risk 0.95, 95% CI 0.86-1.06) compared with matched controls. This suggests that the local proinflammatory environment present in Hashimoto's does not contribute significantly to melanoma risk. Larger studies may be needed to further characterize the relationship between these diseases.

Indexed as

Hashimoto DiseaseMelanomaCohort StudiesHumansRetrospective StudiesRiskTumor MicroenvironmentAutoimmuneCancerHashimoto’s thyroiditisMelanoma

Identifiers

PMID37477680
OpenAlexW4384926212

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.