Evidence map›Paper›PMID 37477667›Full record

ArticleInternational urogynecology journal2024

Does variation of surgical technique affect native tissue anterior pelvic organ prolapse repair outcomes?

Emily Fairclough, Julia Segar, Suzanne Breeman, Anthony Smith, Jenny Myers, Fiona Reid

Open access · hybridAbstract read
In one paragraph

Article in International urogynecology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Emily FaircloughWarrell Unit, St Mary's Hospital, Manchester Foundation Trust, Oxford Road, Manchester, M13 9WL, UK.
Julia SegarInstitute of Population Health, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Suzanne BreemanHealth Services Research Unit, University of Aberdeen, 3rd Floor, Health Sciences Building, Foresterhill, Aberdeen, AB25 2ZD, UK.
Anthony SmithWarrell Unit, St Mary's Hospital, Manchester Foundation Trust, Oxford Road, Manchester, M13 9WL, UK.
Jenny MyersMaternal & Fetal Health Research Centre, Manchester Academic Health Centre, University of Manchester, Manchester, M13 9WL, UK.
Fiona ReidWarrell Unit, St Mary's Hospital, Manchester Foundation Trust, Oxford Road, Manchester, M13 9WL, UK. Fiona.Reid@mft.nhs.uk.
University of Manchester · GBManchester Academic Health Science Centre · GBManchester University NHS Foundation Trust · GBUniversity of Aberdeen · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThe Variation in Surgical Technique study (VaST), demonstrated the large variation in surgical techniques used in native tissue (NT) anterior pelvic organ prolapse (POP) repairs. However, there are few comparative studies of different surgical techniques. This study was aimed at exploring whether surgical technique influenced the outcomes of NT anterior POP repairs.

methodsThe surgical techniques of 22 consultant surgeons performing NT anterior POP repairs were filmed and categorised. These surgeons performed 809 anterior repairs within the PROlapse Surgery: Pragmatic Evaluation and randomised Controlled Trial (PROSPECT). Logistical regression models were used to determine the influence of the different surgical techniques on subjective and objective outcomes, using data collected during PROSPECT.

resultsIn adjusted multivariate linear regression models, fascial-flap repair was associated with an improved subjective outcome (POP-SS) compared with midline plication (β = -2.50 [-4.42 to -0.57]; p = 0.01). At 12 months, separate fascial defect repair was associated with a poorer objective outcome than midline plication (OR 6.06 [1.82-3.52], p = 0.006). At 24 months, deep dissection was associated with a poorer POP-SS than superficial dissection (0.32-2.60, p = 0.0). Continuous-locking closure of the skin was also associated with improved POP-SS compared with continuous non-locking closure (12 months: β = -1.94 [-3.42 to -0.45], p = 0.01).

conclusionSurgical technique may influence the outcome of native tissue anterior POP repairs. Our results should not change practice but inform future research; to develop methods of explicitly recording surgical techniques and allow confirmation of the effect of these aspects of technique on outcome.

Indexed as

ColpotomyPelvic Organ ProlapseFemaleHumansRandomized Controlled Trials as TopicSurgeonsSurgical FlapsTreatment OutcomeNative tissueOutcomePelvic organ prolapseTechnique

Identifiers

PMID37477667
PMCPMC10811059
OpenAlexW4384926298

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.