Evidence map›Paper›PMID 37477126›Full record

ArticleMolecular medicine reports2023

Analysis of glucocorticoid receptor and microRNAs expression in pathological renal tissues.

Anna Angelousi, Georgios Liapis, Maria Gazouli, Ioannis Kofotolios, Stratigoula Sakellariou, Ioannis Boletis, Smaragdi Marinaki

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anna Angelousi1st Department of Internal Medicine, Unit of Endocrinology, Laikon Hospital, 11527 Athens, Greece.
Georgios Liapis1st Department of Pathology, National and Kapodistrian University of Athens, Laikon Hospital, 11527 Athens, Greece.
Maria GazouliLaboratory of Biology, Department of Basic Medical Sciences, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Ioannis KofotoliosDepartment of Nephrology and Renal Transplantation, National and Kapodistrian University of Athens, Laikon Hospital, 11527 Athens, Greece.
Stratigoula Sakellariou1st Department of Pathology, National and Kapodistrian University of Athens, Laikon Hospital, 11527 Athens, Greece.
Ioannis BoletisDepartment of Nephrology and Renal Transplantation, National and Kapodistrian University of Athens, Laikon Hospital, 11527 Athens, Greece.
Smaragdi MarinakiDepartment of Nephrology and Renal Transplantation, National and Kapodistrian University of Athens, Laikon Hospital, 11527 Athens, Greece.
National and Kapodistrian University of Athens · GRLaiko General Hospital of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucocorticoid receptor (GR) is expressed in normal renal podocytes; however, its expression differs among renal diseases. The expression of GR as well as its epigenetic regulators microRNA (miR)30a, miR24 and miR370 was studied in the renal tissues of patients with systemic lupus nephritis (LN), minimal changes disease (MCD) and pauci-immune glumeronephritis (PIN). A total of 51 patients undergoing renal biopsy and 22 nephrectomised controls with no history of parenchymal renal disease were recruited from the Clinic of Nephrology and Renal Transplantation of General Laikon hospital between November 2016 and March 2019. All patients were newly-diagnosed and they were naïve of any treatment. The mRNA and protein expression were analyzed through reverse transcription-quantitative PCR and immunohistochemistry respectively. Written consent was obtained from all participants.

Indexed as

Lupus NephritisMicroRNAsNephrosis, LipoidHumansKidneyReceptors, GlucocorticoidRNA, MessengerMicroRNAsMIRN370 microRNA, humanReceptors, GlucocorticoidRNA, Messengerglucocorticoid receptorminimal changes diseasemiR24miR30amiR370 systemic lupus nephritispauci-immune glumeronephritis

Identifiers

PMID37477126
PMCPMC10433714
OpenAlexW4384924564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.