Evidence map›Paper›PMID 37476727›Full record

ArticleChemical science2023

Semi-enzymatic acceleration of oxidative protein folding by

Shunsuke Okada, Yosuke Matsumoto, Rikana Takahashi, Kenta Arai, Shingo Kanemura, Masaki Okumura, Takahiro Muraoka

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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  4. CaCommunications chemistry · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Shunsuke OkadaDepartment of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology 2-24-16 Naka-cho Koganei Tokyo 184-8588 Japan muraoka@go.tuat.ac.jp.
Yosuke MatsumotoDepartment of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology 2-24-16 Naka-cho Koganei Tokyo 184-8588 Japan muraoka@go.tuat.ac.jp.
Rikana TakahashiDepartment of Chemistry, School of Science, Tokai University Kitakaname Hiratsuka-shi Kanagawa 259-1292 Japan.
Kenta AraiDepartment of Chemistry, School of Science, Tokai University Kitakaname Hiratsuka-shi Kanagawa 259-1292 Japan.ORCID https://orcid.org/0000-0003-0785-2559
Shingo KanemuraSchool of Science, Kwansei Gakuin University 1 Gakuen Uegahara Sanda Hyogo 669-1330 Japan.
Masaki OkumuraFrontier Research Institute for Interdisciplinary Sciences, Tohoku University 6-3 Aramaki-Aza-Aoba, Aoba-ku Sendai 980-8578 Japan okmasaki@tohoku.ac.jp.ORCID https://orcid.org/0000-0001-8130-2470
Takahiro MuraokaDepartment of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology 2-24-16 Naka-cho Koganei Tokyo 184-8588 Japan muraoka@go.tuat.ac.jp.ORCID https://orcid.org/0000-0001-6744-048X
Tokai University · JPTokyo University of Agriculture and Technology · JPKanagawa Institute of Technology · JPKwansei Gakuin University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the first example of a synthetic thiol-based compound that promotes oxidative protein folding upon 1-equivalent loading to the disulfide bonds in the client protein to afford the native form in over 70% yield.

Identifiers

PMID37476727
PMCPMC10355094
OpenAlexW4380987065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.