Evidence map›Paper›PMID 37476531›Full record

ArticleMultidisciplinary respiratory medicine2023

Effects of EPs 7630 on the duration of inability to work in acute bronchitis - a meta-analysis.

Heinrich Matthys, Petra Funk, Andrea Zimmermann, Walter Lehmacher

Open access · goldAbstract read
In one paragraph

Article in Multidisciplinary respiratory medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Heinrich MatthysMedical Director Emeritus, Department of Pneumology, Freiburg University Hospital, Freiburg.
Petra FunkResearch and Development Department, Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe.
Andrea ZimmermannResearch and Development Department, Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe.
Walter LehmacherEmeritus, Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Germany.
Dr Willmar Schwabe (Germany) · DEUniversity Medical Center Freiburg · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute bronchitis (AB) has an enormous economic impact through lost working time. We investigated whether treatment with Methods: A meta-analysis of double-blind, randomized, placebo-controlled trials with adult patients suffering from AB was performed. The average number of days of inability to work and the proportion of patients who were still unable to work after one week's treatment were assessed. Results: Four clinical trials with a total of 1,011 evaluable patients who received the marketed dosage of EPs 7630 (n=505) or placebo (n=506) for seven days were included in the meta-analysis. At baseline, 845/1,011 patients (83.6%) were unable to work. In the four trials, the proportion decreased to between 19 and 14% for EPs 7630 and to between 41 and 55% for placebo (meta-analysis risk ratio and 95% confidence interval: 0.35; 0.26-0.45; p<0.001). For the number of sick days, a weighted mean difference of 1.73 days (1.17-2.29 days; p<0.001) favoring EPs 7630 was observed. Conclusions: For adults suffering from AB, this meta-analysis demonstrates that seven days' treatment with

Indexed as

acute bronchitisadultsEPs 7630inability to workmeta-analysisPelargonium

Identifiers

PMID37476531
PMCPMC10355130
OpenAlexW4380630966

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.