ArticleRoyal Society open science2023
Neural ordinary differential equations with irregular and noisy data.
Article in Royal Society open science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- AI-driven big data analysis and predictive modeling of infectious disease immunity: from correlates to causal, multiscale understanding.Archives of microbiology · 2026Review
- OPTIMIS: Optimizing Personalized Therapies through Integrated Multiscale Intelligent Simulation.bioRxiv : the preprint server for biology · 2026Article
- Neural ordinary differential equations with irregular and noisy data.Royal Society open science · 2023Article
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Authors and funding
2 authors.
Funding
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Abstract
Measurement noise is an integral part of collecting data of a physical process. Thus, noise removal is necessary to draw conclusions from these data, and it often becomes essential to construct dynamical models using these data. We discuss a methodology to learn differential equation(s) using noisy and irregularly sampled measurements. In our methodology, the main innovation can be seen in the integration of deep neural networks with the neural ordinary differential equations (ODEs) approach. Precisely, we aim at learning a neural network that provides (approximately) an implicit representation of the data and an additional neural network that models the vector fields of the dependent variables. We combine these two networks by constraints using neural ODEs. The proposed framework to learn a model describing the vector field is highly effective under noisy measurements. The approach can handle scenarios where dependent variables are unavailable at the same temporal grid. Moreover, a particular structure, e.g. second order with respect to time, can easily be incorporated. We demonstrate the effectiveness of the proposed method for learning models using data obtained from various differential equations and present a comparison with the neural ODE method that does not make any special treatment to noise. Additionally, we discuss an ensemble approach to improve the performance of the proposed approach further.
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Registered trials
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