Evidence map›Paper›PMID 37476397›Full record

ArticleAdvanced nanobiomed research2023

Novel Helical Trp- and Arg-Rich Antimicrobial Peptides Locate Near Membrane Surfaces and Rigidify Lipid Model Membranes.

Saheli Mitra, Mark Coopershlyak, Yunshu Li, Bhairavi Chandersekhar, Rachel Koenig, Mei-Tung Chen, Brandt Evans, Frank Heinrich, Berthony Deslouches, Stephanie Tristram-Nagle

Open access · goldAbstract read
In one paragraph

Article in Advanced nanobiomed research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. ThebioRxiv : the preprint server for biology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. The AAA+ protein Msp1 recognizes substrates by a hydrophobic mismatch.bioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Killing ofMicroorganisms · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Saheli MitraBiological Physics Group Physics Department Carnegie Mellon University Pittsburgh, PA 15213, USA.
Mark CoopershlyakBiological Physics Group Physics Department Carnegie Mellon University Pittsburgh, PA 15213, USA.
Yunshu LiBiological Physics Group Physics Department Carnegie Mellon University Pittsburgh, PA 15213, USA.
Bhairavi ChandersekharBiological Physics Group Physics Department Carnegie Mellon University Pittsburgh, PA 15213, USA.
Rachel KoenigBiological Physics Group Physics Department Carnegie Mellon University Pittsburgh, PA 15213, USA.
Mei-Tung ChenBiological Physics Group Physics Department Carnegie Mellon University Pittsburgh, PA 15213, USA.
Brandt EvansBiological Physics Group Physics Department Carnegie Mellon University Pittsburgh, PA 15213, USA.
Frank HeinrichBiological Physics Group Physics Department Carnegie Mellon University Pittsburgh, PA 15213, USA.
Berthony DeslouchesDepartment of Environmental and Occupational Health University of Pittsburgh Pittsburgh, PA 15261, USA.
Stephanie Tristram-NagleBiological Physics Group Physics Department Carnegie Mellon University Pittsburgh, PA 15213, USA.
Carnegie Mellon University · USNational Institute of Standards and Technology · USUniversity of Pittsburgh · US

Funding

Training and OutreachP30GM124166 · NIGMS · CORNELL UNIVERSITY · PI RICHARD A. CERIONE · 2019 to 2026
$28.3M
Structural determinants of activity and mechanism of cationic peptide antibiotic activity against colistin-resistant bacteriaR01AI172861 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Berthony Deslouches · 2023 to 2026
$2.5M
Determinants and Mechanisms of Efficacy of Peptide Antibiotics as Novel Sepsis TherapyR01GM125917 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DESLOUCHES, BERTHONY · 2018 to 2022
$2.1M
NIAID NIH HHS R01 AI172861NIGMS NIH HHS P30 GM124166NIGMS NIH HHS R01 GM125917
6 · The paper itself

Abstract

Antibiotics are losing effectiveness as bacteria become resistant to conventional drugs. To find new alternatives, antimicrobial peptides (AMPs) are rationally designed with different lengths, charges, hydrophobicities (

Indexed as

antimicrobial peptides (AMPs)circular dichroism (CD)elasticityGram-negative bacteriaGram-positive bacteriaminimum inhibitory concentration (MIC)X-ray diffuse scattering (XDS)

Identifiers

PMID37476397
PMCPMC10358585
OpenAlexW4365814399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.