Evidence map›Paper›PMID 37476375›Full record

ArticleFrontiers in oncology2023

Leptospermum extract (QV0) suppresses pleural mesothelioma tumor growth

Huaikai Shi, Le Zhang, Ta-Kun Yu, Ling Zhuang, Helen Ke, Ben Johnson, Emma Rath, Kenneth Lee, Sonja Klebe, Steven Kao and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Huaikai ShiAsbestos and Dust Diseases Research Institute, Sydney, NSW, Australia.
Le ZhangInstitute for Biomedical Materials & Devices (IBMD), Faculty of Science, The University of Technology, Sydney, NSW, Australia.
Ta-Kun YuAsbestos and Dust Diseases Research Institute, Sydney, NSW, Australia.
Ling ZhuangAsbestos and Dust Diseases Research Institute, Sydney, NSW, Australia.
Helen KeAsbestos and Dust Diseases Research Institute, Sydney, NSW, Australia.
Ben JohnsonAsbestos and Dust Diseases Research Institute, Sydney, NSW, Australia.
Emma RathGiannoulatou Laboratory, Victor Chang Cardiac Research Institute, Sydney, NSW, Australia.
Kenneth LeeSydney Medical School, University of Sydney, Sydney, NSW, Australia.
Sonja KlebeAsbestos and Dust Diseases Research Institute, Sydney, NSW, Australia.
Steven KaoAsbestos and Dust Diseases Research Institute, Sydney, NSW, Australia.
Karl Lijun QinQuality Global Supply Pty. Ltd., Tuggerah, NSW, Australia.
Hong Ngoc Thuy PhamCollege of Engineering, Science and the Environment, University of Newcastle, Sydney, NSW, Australia.
Quan VuongCollege of Engineering, Science and the Environment, University of Newcastle, Sydney, NSW, Australia.
Yuen Yee ChengInstitute for Biomedical Materials & Devices (IBMD), Faculty of Science, The University of Technology, Sydney, NSW, Australia.
Asbestos Diseases Research Institute · AUUniversity of Newcastle Australia · AUUniversity of Technology Sydney · AUChris O’Brien Lifehouse · AUFlinders Medical Centre · AUUniversity of Sydney · AUVictor Chang Cardiac Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pleural mesothelioma (PM) is a highly aggressive, fast-growing asbestos-induced cancer with limited effective treatments. There has been interest in using naturally occurring anticancer agents derived from plant materials for the treatment of PM. However, it is unclear if an aqueous extract from

Indexed as

anti-cancer (anticancer) drugsapoptosisLeptospermummitochondria dysfunctionpleural mesothelioma

Identifiers

PMID37476375
PMCPMC10354640
OpenAlexW4383198771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.