ArticleMovement disorders clinical practice2023
Brain Bank Questionnaire Helps in Differential Diagnosis of Movement Disorders: An Autopsy Study of 150 Patients.
Article in Movement disorders clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Intrinsic capacity in Lewy body dementia: a review.The Journal of frailty & aging · 2025Review
- Frontotemporal Lobar degeneration with TDP-43 presenting as progressive supranuclear palsy syndrome.Acta neuropathologica communications · 2025Article
- Evaluating the performance of large language models: ChatGPT and Google Bard in generating differential diagnoses in clinicopathological conferences of neurodegenerative disorders.Brain pathology (Zurich, Switzerland) · 2024Article
- Validation Study of the MDS Criteria for the Diagnosis of Multiple System Atrophy in the Mayo Clinic Brain Bank.Neurology · 2023Article
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5 authors.
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Abstract
Background: As part of the CurePSP brain donation program, a questionnaire was developed to gather basic clinical information on donors; however, its usefulness has not been evaluated. Objective: To assess the value of information obtained from the questionnaire in differentiating between parkinsonian disorders. Methods: We reviewed 150 questionnaires, including 50 patients, each with a neuropathologic diagnosis of Lewy body disease (LBD), multiple system atrophy (MSA), or progressive supranuclear palsy. The frequency of clinical features recorded in the questionnaires was compared for the three disorders, and a machine learning algorithm was used to identify features predicting neuropathologic diagnosis. Results: The information from the questionnaires correlated with core clinical features for each disorder, such as hallucinations for LBD and autonomic dysfunction for MSA. Hallucinations and disorientations were identified as the key variables that contributed most to the prediction of neuropathology. Conclusion: The questionnaire provides useful clinical information for clinicopathological correlative studies.
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