Evidence map›Paper›PMID 37476315›Full record

ArticleMovement disorders clinical practice2023

Expiratory Muscle Strength Training in Multiple System Atrophy: A Pilot Study.

Martin Srp, Tereza Bartosova, Jiri Klempir, Rebeka Lagnerova, Ota Gal, Tereza Listvanova, Robert Jech, Evzen Ruzicka, Martina Hoskovcova

2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06585332 completednot on this mapstarted 2024, after this paper: background citation

Hand Grip Strength As a Screening Tool for Respiratory Dysfunction in Huntington's Disease

TypeobservationalSponsorGeneral University Hospital, PragueRan2024 to 2024Enrolled70ConditionsHuntington DiseaseArmsAssessment of respiratory paramenters (Maximal inspiratory pressure, maximal expiratory pressure, and voluntary peak cough flow))
NCT06942533 narecruitingnot on this mapstarted 2025, after this paper: background citation

The Effect of Visual Feedback From the SpiroGym Mobile Application on Expiratory Muscle Strength Training Performance in Patients With Parkinson's Disease

TypeinterventionalSponsorGeneral University Hospital, PragueRan2025 to 2026Enrolled30ConditionsParkinson Disease, Breathing Exercises, TelemedicineArmsEMST with SpiroGym app, EMST without SpiroGym app
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Martin SrpDepartment of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague Prague Czech Republic.
Tereza BartosovaDepartment of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague Prague Czech Republic.
Jiri KlempirDepartment of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague Prague Czech Republic.
Rebeka LagnerovaDepartment of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague Prague Czech Republic.
Ota GalDepartment of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague Prague Czech Republic.
Tereza ListvanovaDepartment of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague Prague Czech Republic.
Robert JechDepartment of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague Prague Czech Republic.ORCID https://orcid.org/0000-0002-9732-8947
Evzen RuzickaDepartment of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague Prague Czech Republic.
Martina HoskovcovaDepartment of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague Prague Czech Republic.
Charles University · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The effects of expiratory muscle strength training (EMST) has not yet been investigated in MSA patients. Objective: The primary objective was to test the effects of EMST on expiratory muscle strength and voluntary peak cough flow (vPCF) in patients with multiple system atrophy (MSA). The secondary objective was to assess the suitability of the pulmonary dysfunction index as a tool for identifying MSA patients with expiratory muscle weakness and reduced voluntary peak cough flow. Methods: This was an open label, non-controlled study, with an 8-week intensive home-based EMST protocol. The outcome measures included: maximal expiratory pressure (MEP) and vPCF. The sensitivity and specificity of the index of pulmonary dysfunction in the respiratory diagnostic process were assessed using receiver operating characteristic (ROC) analysis. Results: Fifteen MSA patients were enrolled in the study. Twelve MSA patients completed the training period. After the training period, MEP significantly increased ( Conclusions: These findings indicate non-significant differences in vPCF after 8 weeks of EMST. The index of pulmonary dysfunction appears to be a promising prognostic screening tool for identifying altered cough efficacy in MSA patients. Test cut-offs may be used to select an appropriate respiratory physiotherapy technique.

Indexed as

expiratory muscle strength trainingmaximum expiratory pressuremultiple system atrophyvoluntary peak cough flow

Identifiers

PMID37476315
PMCPMC10354620
OpenAlexW4372288021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.