Evidence map›Paper›PMID 37476068›Full record

ArticleBioengineering & translational medicine2023

Soluble CD80 oral delivery by recombinant Lactococcus suppresses tumor growth by enhancing antitumor immunity.

Ziqing Lin, Yanqing Tang, Zerong Chen, Simin Li, Xueyan Xu, Xufeng Hou, Zhenhui Chen, Junjie Wen, Weisen Zeng, Xiaojing Meng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Bioengineering & translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Ziqing LinDepartment of Cell Biology, School of Basic Medicine Southern Medical University Guangzhou China.
Yanqing TangDepartment of Cell Biology, School of Basic Medicine Southern Medical University Guangzhou China.
Zerong ChenDepartment of Cell Biology, School of Basic Medicine Southern Medical University Guangzhou China.
Simin LiDepartment of Cell Biology, School of Basic Medicine Southern Medical University Guangzhou China.
Xueyan XuDepartment of Cell Biology, School of Basic Medicine Southern Medical University Guangzhou China.
Xufeng HouDepartment of Cell Biology, School of Basic Medicine Southern Medical University Guangzhou China.
Zhenhui ChenDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health Southern Medical University Guangzhou China.
Junjie WenGuangzhou Weisengene Biological Technology Co., Ltd. Guangzhou China.
Weisen ZengDepartment of Cell Biology, School of Basic Medicine Southern Medical University Guangzhou China.
Xiaojing MengDepartment of Occupational Health and Occupational Medicine, School of Public Health Southern Medical University Guangzhou Guangdong China.
Hongying FanDepartment of Microbiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health Southern Medical University Guangzhou China.ORCID https://orcid.org/0000-0002-0725-1596
Southern Medical University · CNNanfang Hospital · CNAtotech (United States) · USGuangzhou Electronic Technology (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD80 is an important co-stimulatory molecule that participates in the immune response. Soluble CD80 can induce T cell activation and overcome PDL1-mediated immune suppression. In this study, we aimed to construct recombinant

Indexed as

cholera toxin B subunit (CTB)human soluble CD80lactic acid bacteriatumor therapy

Identifiers

PMID37476068
PMCPMC10354755
OpenAlexW4382448931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.