Evidence map›Paper›PMID 37475864›Full record

ReviewFrontiers in immunology2023

Interplay between RNA interference and transposable elements in mammals.

Alexis Cornec, Enzo Z Poirier

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Challenges and Opportunities Arising from Host-International journal of molecular sciences · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. CRISPR deletion of a SINE-VNTR-Frontiers in neurology · 2023
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexis CornecStem Cell Immunity Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.
Enzo Z PoirierStem Cell Immunity Team, Institut Curie, PSL Research University, INSERM U932, Paris, France.
Université Paris Sciences et Lettres · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RNA interference (RNAi) plays pleiotropic roles in animal cells, from the post-transcriptional control of gene expression via the production of micro-RNAs, to the inhibition of RNA virus infection. We discuss here the role of RNAi in regulating the expression of self RNAs, and particularly transposable elements (TEs), which are genomic sequences capable of influencing gene expression and disrupting genome architecture. Dicer proteins act as the entry point of the RNAi pathway by detecting and degrading RNA of TE origin, ultimately leading to TE silencing. RNAi similarly targets cellular RNAs such as repeats transcribed from centrosomes. Dicer proteins are thus nucleic acid sensors that recognize self RNA in the form of double-stranded RNA, and trigger a silencing RNA interference response.

Indexed as

DNA Transposable ElementsRNA, Double-StrandedAnimalsMammalsRNA InterferenceRNA, Small InterferingDNA Transposable ElementsRNA, Double-StrandedRNA, Small InterferingDicer (Dicer1)epigeneticsmammalspathogen-associated molecular pattern (PAMP)pattern recognition receptor (PRR)RNA interferencetransposable elements

Identifiers

PMID37475864
PMCPMC10354258
OpenAlexW4383224122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.