Evidence map›Paper›PMID 37475843›Full record

ReviewWorld journal of gastroenterology2023

Mortality from chronic liver disease: Recent trends and impact of the COVID-19 pandemic.

Ugo Fedeli, Claudio Barbiellini Amidei, Veronica Casotto, Enrico Grande, Mario Saia, Alberto Zanetto, Francesco Paolo Russo

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
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  14. The burden of metabolic dysfunction-associated steatotic liver disease and viral hepatitis in Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024
    Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ugo FedeliEpidemiological Department, Azienda Zero, Veneto Region, Padova 35132, Italy. ugo.fedeli@azero.veneto.it.
Claudio Barbiellini AmideiEpidemiological Department, Azienda Zero, Veneto Region, Padova 35132, Italy.
Veronica CasottoEpidemiological Department, Azienda Zero, Veneto Region, Padova 35132, Italy.
Enrico GrandeIntegrated System for Health, Social Assistance and Welfare, National Institute of Statistics, Rome 00184, Italy.
Mario SaiaClinical Governance, Azienda Zero, Veneto Region, Padova 35132, Italy.
Alberto ZanettoDepartment of Surgery Oncology and Gastroenterology, University of Padua, Padova 35128, Italy.
Francesco Paolo RussoDepartment of Surgery Oncology and Gastroenterology, University of Padua, Padova 35128, Italy.
Regione del Veneto · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prepandemic time trends in mortality from chronic liver disease (CLD) differed according to specific cause of death (decreasing for liver cirrhosis, stable or increasing for liver cancer), etiology (increasing for nonalcoholic fatty liver disease, generally decreasing for other etiologies), and world region (decreasing in areas with the highest burden of hepatitis B virus, increasing in Eastern Europe and other countries). The coronavirus disease 2019 (COVID-19) pandemic affected mortality of patients with CLD both directly, with a higher risk for severe illness and death depending on age, stage and etiology of the disease, and indirectly, through social isolation and loss of support, harmful drinking, and difficulties in access to care. Nevertheless, only sparse data are available on variations in CLD as a cause of death during the pandemic. In the USA, in 2020-2021 a growth in mortality was registered for all liver diseases, more marked for alcoholic liver disease, especially among young people aged 25-44 years and in selected ethnic groups. COVID-19 related deaths accounted only for a minor part of the excess. Further data from mortality registers of other countries are warranted, preferably adopting the so-called multiple cause-of-death approach, and extended to deaths attributed to viral hepatitis and liver cancer.

Indexed as

COVID-19Liver Diseases, AlcoholicLiver NeoplasmsNon-alcoholic Fatty Liver DiseaseAdolescentHumansLiver CirrhosisPandemicsChronic liver diseaseCOVID-19Liver cancerLiver cirrhosisMortalityMultiple causes of death

Identifiers

PMID37475843
PMCPMC10354574
OpenAlexW4383336791

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.