ArticleJournal of translational medicine2023
Association between periodontitis and the prevalence and prognosis of prediabetes: a population-based study.
Article in Journal of translational medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- Periodontitis and all-cause mortality in 60- and 66-year-old individuals: a 23-year prospective cohort study.Acta odontologica Scandinavica · 2026Article
- Causal role of serum metabolites in chronic periodontitis: A bidirectional Mendelian randomization and multi-omics integration study.Medicine · 2026Article
- Salivary microbiota and clinical periodontal measures predicting cardiometabolic disease mortality: A nationwide survey.Journal of periodontology · 2026Article
- The role of Triglyceride-Glucose index in predicting pre-DM risk among Chinese adults.Scientific reports · 2025Article
- Association between adjustable dietary factors and periodontitis: NHANES 2009-2014 and Mendelian randomization.Journal of translational medicine · 2025Article
- Clinical and radiographic peri-implant parameters in type-2 diabetic and non-diabetic individuals with major depressive disorder.Scientific reports · 2025Article
- Neutrophil-lymphocyte ratio is a predictor for all-cause and cardiovascular mortality in individuals with prediabetes in a National study.Endocrine · 2025Article
- Effects of Endurance Training and Chlorogenic Acid on Oxidative and Nitrosative Stress Markers in Prediabetic Male Mice.International journal of preventive medicine · 2025Article
- Link between periodontitis and diabetic retinopathy: Inflammatory pathways and clinical implications.World journal of diabetes · 2024Article
- Association of periodontitis with cardiovascular and all-cause mortality in hypertensive individuals: insights from a NHANES cohort study.BMC oral health · 2024Article
- Convolutional neural networks combined with classification algorithms for the diagnosis of periodontitis.Oral radiology · 2024Article
- Clinical attachment loss is cross-sectionally associated with elevated glucose among adults without diabetes.Journal of clinical periodontology · 2024Article
- Associations between single and multiple dietary vitamins and the risk of periodontitis: results from NHANES 2009-2014.Frontiers in nutrition · 2024Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiagnosis and intervention of prediabetes is an emerging method for preventing diabetic progression and complications. Periodontitis has been reported to strongly correlate with the dysregulation of glucose metabolism. Nonetheless, the relationship between periodontal status and the prevalence of prediabetes as well as its prognosis remains elusive. This study aimed to investigate the association of periodontitis with the prevalence of prediabetes and furtherly explore the all-cause mortality of different periodontal status among patients with prediabetes.
methodsThe dateset from the National Health and Nutrition Examination Survey (NHANES) was utilized for our study. Participants were divided into two groups (with or without periodontitis) and further assigned into subgroups by different grades of periodontitis to analyze the association between periodontitis and prevalence of prediabetes. Then we analyzed the association between all-cause mortality and periodontitis among patients with prediabetes. Weighted multivariate logistic/Cox regression models were adopted in our study.
resultsA total of 15390 participants were included and divided into a periodontitis group (n = 5033) and a nonperiodontitis group (n = 10357). The results showed that participants with periodontitis had a higher risk of prediabetes. After adjusting for covariables, more severe periodontitis was positively related to prediabetes (moderate vs. no periodontitis: OR = 1.46, 95% CI: 1.29-1.65; severe vs. no periodontitis: OR = 1.62, 95% CI 1.31-2.01). Furtherly, we explored the association between all-cause mortality and periodontal status among patients diagnosed with prediabetes (n = 4518) and found that severe (HR = 1.806, 95% CI 1.19-2.74) and moderate periodontitis (HR = 2.42, 95% CI 1.95-3.01) were associated with elevated all-cause mortality among patients with prediabetes.
conclusionsIn general, the results suggest that periodontitis is positively associated with the prevalence and mortality of prediabetes. These results suggest that good management of periodontal status could be a potential strategy to reduce the occurrence and development of prediabetes.
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