ReviewNature reviews. Cardiology2023
De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis.
Registry-linked trialOpen access · bronzeAbstract readReviewConsensus Statement
In one paragraph
Review in Nature reviews. Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04755387 (EASTYLE), which is not on this map. Cited by 43 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
15.8field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
EASTYLE (DE-escAlation Strategy for Optimal Ticagrelor Therapy in Acute MYocardiaL Infarction PatiEnts, Prospective, Multicenter, Randomized) Trial
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Antiplatelet therapy in acute coronary syndrome: a systematic critical appraisal of current guidelines.BMC cardiovascular disorders · 2026Pooled it
- Efficacy and safety of dual antiplatelet therapy de-escalation in East Asian individuals following percutaneous coronary intervention for acute coronary syndrome: a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Invasive Strategy With Intended Percutaneous Coronary Intervention Versus Conservative Treatment in Older People With ST-Segment-Elevation Myocardial Infarction: A Meta-Analysis.Journal of the American Heart Association · 2025Pooled it
- Picropodophyllotoxin Suppresses Factor Xa Activity, Platelet Aggregation, and Arterial Thrombosis.Biomolecules · 2026Article
- Platelet FcɣRIIa Expression Refines Clinical Risk Assessment After Myocardial Infarction.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026Article
- Clopidogrel Vs Aspirin Monotherapy for Secondary Prevention After Percutaneous Coronary Intervention: A Nationwide Cohort Study.JACC. Asia · 2026Article
- Abbreviated dual antiplatelet therapy after percutaneous coronary intervention with drug coated balloons in acute coronary syndromes: insights from the SWEDEHEART registry.European heart journal. Cardiovascular pharmacotherapy · 2026Observational
- Transformer-DAPT: AI-based dynamic assessment of ischemic and bleeding risks in patients on DAPT following PCI.NPJ digital medicine · 2026Article
- Article
- Recent advances in percutaneous coronary intervention for modernizing coronary physiology-guided and device-based strategies for coronary revascularization.Frontiers in medicine · 2026Review
- Research progress on de-escalation strategies of dual antiplatelet therapy after acute coronary syndrome.Frontiers in medicine · 2026Article
- Impact of antiplatelet therapy on erectile dysfunction following percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction.Frontiers in medicine · 2026Article
- Coronary Artery Revascularization in the Older Adult Population: A Scientific Statement From the American Heart Association.Circulation · 2025Review
- High-Bleeding-Risk Criteria as a Modifier of Treatment Effect During Antithrombotic Therapy.Korean circulation journal · 2025Article
- Prevention of acute thrombosis with vascular endothelium antioxidative nanoscavenger.Nature nanotechnology · 2025Article
- Bleeding in Antiplatelet Therapy: A Narrative Review of Clinical Evidence and the Roles of Pharmacists and Nurses.Reviews in cardiovascular medicine · 2025Review
- Ethnicity, P2YJACC. Asia · 2025Article
- Personalized Treatment of Patients with Coronary Artery Disease: The Value and Limitations of Predictive Models.Journal of cardiovascular development and disease · 2025Review
- Decoding Bleeding Risks and Survival in Patients Undergoing Percutaneous Coronary Intervention on Antiplatelet Therapy.JACC. Asia · 2025Review
- Multiple biomarkers risk score for accurately predicting the long-term prognosis of patients with acute coronary syndrome.Journal of geriatric cardiology : JGC · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors at 18 institutions in 16 countries.
Diana A Gorog *Faculty of Medicine, National Heart and Lung Institute, Imperial College, London, UK. d.gorog@imperial.ac.uk.ORCID 0000-0002-9286-1451
Jose Luis Ferreiro *Department of Cardiology, Hospital Universitario de Bellvitge, CIBERCV, L'Hospitalet de Llobregat, Spain.ORCID 0000-0003-1202-9575
Ingo AhrensDepartment of Cardiology and Medical Intensive Care, Augustinerinnen Hospital Cologne, Academic Teaching Hospital University of Cologne, Cologne, Germany.
Junya AkoDepartment of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan.ORCID 0000-0001-6645-6404
Tobias GeislerDepartment of Cardiology and Angiology, University Hospital, Eberhard-Karls-University Tuebingen, Tuebingen, Germany.
Sigrun HalvorsenDepartment of Cardiology, Oslo University Hospital Ulleval, Oslo, Norway.
Kurt Huber3rd Department of Medicine, Cardiology and Intensive Care Medicine, Wilhelminen Hospital, Vienna, Austria.ORCID 0000-0002-7934-5524
Young-Hoon JeongCAU Thrombosis and Biomarker Center, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Republic of Korea.ORCID 0000-0003-0403-3726
Eliano P NavareseInterventional Cardiology and Cardiovascular Medicine Research, Department of Cardiology and Internal Medicine, Nicolaus Copernicus University, Bydgoszcz, Poland.
Andrea RubboliDepartment of Emergency, Internal Medicine and Cardiology, Division of Cardiology, S. Maria delle Croci Hospital, Ravenna, Italy.
Dirk SibbingLudwig-Maximilians University München, Munich, Germany.
Jolanta M Siller-MatulaDepartment of Cardiology, Austria Medical University of Vienna, Vienna, Austria.
Robert F StoreyCardiovascular Research Unit, Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, UK.ORCID 0000-0002-6677-6229
Jack W C TanNational Heart Centre Singapore and Sengkang General Hospital, Singapore, Singapore.
Jurrien M Ten BergSt Antonius Hospital, Nieuwegein, The Netherlands.
Marco ValgimigliCardiocentro Institute, Ente Ospedaliero Cantonale, Università della Svizzera Italiana (USI), Lugano, Switzerland.
Christophe VandenbrieleDepartment of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
Gregory Y H LipLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University, Liverpool, UK.ORCID 0000-0002-7566-1626
Bellvitge University Hospital · ESChung-Ang University · KRGerman Centre for Cardiovascular Research · DEKitasato University · JPKU Leuven · BEMaastricht University · NLMedical University of Vienna · ATNational Heart Centre Singapore · SGOslo University Hospital · NOOspedale "Santa Maria delle Croci" di Ravenna · ITSigmund Freud Privatuniversität Wien · ATUniversity of Alberta · CAUniversity of Bern · CHUniversity of Freiburg · DEUniversity of Hertfordshire · GBUniversity of Liverpool · GBUniversity of Sheffield · GBUniversity of Tübingen · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y purinoceptor 12 (P2Y
Indexed as
Acute Coronary SyndromeCoronary ThrombosisPercutaneous Coronary InterventionAspirinHemorrhageHumansPlatelet Aggregation InhibitorsPrasugrel HydrochloridePurinergic P2Y Receptor AntagonistsTreatment OutcomeAspirinPlatelet Aggregation InhibitorsPrasugrel HydrochloridePurinergic P2Y Receptor Antagonists
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT04755387ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.