ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2023
A paraventricular thalamus to insular cortex glutamatergic projection gates "emotional" stress-induced binge eating in females.
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 26 citations in OpenAlex.
- The Neural Network of Orexin-A: Implications in Feeding Regulation and Obesity-Anxiety Comorbidity.Brain sciences · 2026Review
- Review
- Independent role of alexithymia on weight loss outcomes in obese women: a six month follow-up study.BMC women's health · 2026Article
- Translational Perspectives on Binge-Eating: Insights from Animal Models.Current psychiatry reports · 2026Review
- Glutamatergic dysfunction of astrocytes in paraventricular nucleus of thalamus contributes to adult anxiety susceptibility in adolescent ethanol exposed mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- The encoding of interoceptive-based predictions by the paraventricular nucleus of the thalamus D2R+ neurons.iScience · 2026Article
- Influence of caloric restriction history, intermittent exposure to palatable food and sex in a binge eating model in C57BL/6J mice.Journal of eating disorders · 2025Article
- Regulation of addiction by the insular cortex: The interplay between interoception and cognitive function.iScience · 2025Review
- Dissection of Neurochemical Pathways Across Complexity and Scale.Journal of neurochemistry · 2025Review
- Relaxin family peptide receptor 3 (RXFP3) expressing cells in the zona incerta/lateral hypothalamus augment behavioural arousal.Journal of neurochemistry · 2025Article
- Microbiota-gut-brain axis in binge-eating disorder: Towards microbiome-based therapies.Neuroscience applied · 2024Review
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Authors and funding
13 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well-established that stress and negative affect trigger eating disorder symptoms and that the brains of men and women respond to stress in different ways. Indeed, women suffer disproportionately from emotional or stress-related eating, as well as associated eating disorders such as binge eating disorder. Nevertheless, our understanding of the precise neural circuits driving this maladaptive eating behavior, particularly in women, remains limited. We recently established a clinically relevant model of 'emotional' stress-induced binge eating whereby only female mice display binge eating in response to an acute "emotional" stressor. Here, we combined neuroanatomic, transgenic, immunohistochemical and pathway-specific chemogenetic approaches to investigate whole brain functional architecture associated with stress-induced binge eating in females, focusing on the role of Vglut2 projections from the paraventricular thalamus (PVT
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.