ArticleGeneral thoracic and cardiovascular surgery2024
Can modified frailty index predict postoperative complication after lung cancer surgery?
Article in General thoracic and cardiovascular surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Frailty profiles and symptomatic radiation pneumonitis in patients with lung cancer undergoing radiotherapy: A latent class analysis.Asia-Pacific journal of oncology nursing · 2026Article
- Association between daily step counts and frailty trajectory classes in lung cancer patients undergoing radiotherapy: a prospective longitudinal study.Journal of cancer survivorship : research and practice · 2026Article
- Study on key markers of NETosis: predictive indicator for postoperative frailty following complete cytoreductive surgery in advanced ovarian cancer.Frontiers in immunology · 2026Article
- Predictive value of modified frailty index-5 to major complications after videothoracoscopic pulmonary resections.Updates in surgery · 2025Article
- Psoas muscle index as a novel measure of frailty and predictor of post-operative outcome in octogenarians with non-small cell lung cancer.Journal of thoracic disease · 2025Article
- The prognostic significance of modified frailty index-5 in patients undergoing pneumonectomy for lung cancer.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
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Abstract
purposeThe impact of the modified frailty index (mFI) on postoperative complications after lung cancer surgery was investigated.
methodsPatients who underwent lung cancer surgery in 2017 were included. 30-day postoperative mortality and morbidity were evaluated according to their Clavien-Dindo classification. mFI values are presented as the sum of values of 11 included items. Logistic regression was used to assess the effect of mFI on postoperative severe complication incidence.
resultsAmong 190 patients considered, severe postoperative complications (Grade 3 or more) were observed in 30 (16%). No patients died within 30 days of surgery. The incidence of severe complications was 3.6% in patients with mFI of 0, 16.2% in patients with mFI of 1, 23.4% in patients with mFI of 2, and 31.6% in patients with mFI of 3 or more, and was correlated with the grade of mFI. Univariate and multivariate analyses showed that the high mFI was significantly predictive of postoperative complications. Frail patients of mFI ≥ 2 were at 3.0-fold greater risk of severe complications than non-frail patients of mFI 0 or 1.
conclusionmFI was associated with morbidity after lung cancer surgery. Preoperative frailty assessment and appropriate intervention to frail patients would be required to improve postoperative outcomes.
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