ArticleEvidence-based dentistry2023
Is there any link between periodontitis and inflammatory bowel diseases?
Article in Evidence-based dentistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- The impact of systemic administration of polyphenols on periodontitis associated with diabetes mellitus: a systematic review.Acta odontologica Scandinavica · 2024Pooled it
- Impact of anti-TNF and anti-IL-12/IL-23 antibody therapy on periodontal inflammation and gingival crevicular fluid IL-6 in patients with inflammatory bowel diseases.Frontiers in immunology · 2026Article
- Does periodontitis have any association with mild cognitive impairment?Evidence-based dentistry · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
designThis was an analytical 'case-control' study. CASE/CONTROL SELECTION: Patients diagnosed with inflammatory bowel diseases (IBD), that is either ulcerative colitis or Crohn's disease, were selected from the Medical Hospital of University of Turin and were referred as cases. Equal number of patients, not having IBD, were selected from the Dental school of the same University and called as controls. The cases and controls were matched for age, sex, and ethnicity. Data for all patients regarding their socio-demographic features was collected using a questionnaire. In addition, data regarding periodontal health, which included clinical attachment loss, bleeding on probing, recession, presence, and severity of periodontitis etc. was also evaluated for all the included patients. DATA ANALYSIS: Data analysis involved descriptive statistics to compare cases and control. This was done by comparing the proportions (using χ
resultsNon-significant differences were observed on comparing various socio-demographic features while significant differences were observed in the prevalence of severe periodontitis (85.6% vs. 65.6%) amongst cases and controls. Fragmenting the periodontitis-prevalence data as per age, patients in age groups 36-50 and 51-65 exhibited significant differences on comparing cases and controls, with p values of 0.002 and 0.022, respectively, while comparison of periodontitis prevalence amongst cases/controls in 18-35 age group or >65 age group non-significant differences were observed. The logistic regression models revealed strong associations between IBD and periodontitis and vice versa. Role of other risk factors was also explored in these regression models.
conclusionsAssociations between periodontitis and IBD were found; and these connotations were bi-directional.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.