Evidence map›Paper›PMID 37474169›Full record

ArticleBMJ open2023

Manchester Intermittent and Daily diet Type 1 Diabetes App Study (MIDDAS-Type 1): protocol for a randomised feasibility trial of an intermittent and continuous low-energy diet in patients with type 1 diabetes and overweight and obesity.

Sarah McDiarmid, Michelle Harvie, Azza Aglan, Hannah Winterbottom, Womba Mubita, Amanda Hulme, Jane Davies, James Yates, Suzanne Krizak, Diane Perry and 1 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04674384 (A Randomised Feasibility Trial of an Intermittent Low Energy Diet), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04674384 naunknown statusnot on this map

A Randomised Feasibility Trial of an Intermittent Low Energy Diet (ILED) and Continuous Low Energy Diet (CLED) in Patients With Type 1 Diabetes and Obesity

TypeinterventionalSponsorManchester University NHS Foundation TrustRan2022 to 2024Enrolled12ConditionsType 1 Diabetes, ObesityArmsOptifast meal replacement shakes
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sarah McDiarmidResearch Dietitians, Manchester University NHS Foundation Trust, Manchester, UK sarahmcdiarmid@nhs.net.ORCID 0000-0002-7668-7860
Michelle HarvieThe Prevent Breast Cancer Research Unit Research Dietitians, Manchester University NHS Foundation Trust, Manchester, UK.ORCID 0000-0001-9761-3089
Azza AglanGreater Manchester Mental Health NHS Foundation Trust, Manchester, UK.ORCID 0000-0001-5756-397X
Hannah WinterbottomResearch Dietitians, Manchester University NHS Foundation Trust, Manchester, UK.ORCID 0000-0001-9944-8697
Womba MubitaDepartment of Endocrinology and Diabetes, Manchester University NHS Foundation Trust, Manchester, UK.ORCID 0000-0001-6362-9883
Amanda HulmeDepartment of Endocrinology and Diabetes, Manchester University NHS Foundation Trust, Manchester, UK.ORCID 0000-0001-9823-0725
Jane DaviesManchester University NHS Foundation Trust, Manchester, UK.ORCID 0000-0001-6366-9324
James YatesManchester University NHS Foundation Trust, Manchester, UK.
Suzanne KrizakManchester University NHS Foundation Trust, Manchester, UK.
Diane PerryPatient Representative, Manchester University NHS Foundation Trust, Manchester, UK.
Basil G IssaDepartment of Endocrinology and Diabetes, Manchester University NHS Foundation Trust, Manchester, UK.ORCID 0000-0001-5681-2698
Manchester University NHS Foundation Trust · GBGreater Manchester Mental Health NHS Foundation Trust · GB

Funding

Department of Health
6 · The paper itself

Abstract

introductionRising levels of overweight and obesity among people with type 1 diabetes (T1D) contribute to insulin resistance, dyslipidaemia, retinopathy, cardiometabolic complications and psychological morbidity. Continuous low-energy diets (CLED) providing approximately 800 kcal (3347 kJ)/day can produce significant weight loss in type 2 diabetes, and intermittent low-energy diets (ILED) may be an alternative. The Manchester Intermittent and Daily diet Type 1 Diabetes App Study (MIDDAS-Type 1) aims to assess the safety, acceptability and feasibility of remotely delivered ILED and CLED programmes for people with T1D and overweight and obesity. METHODS AND ANALYSIS: Twelve participants with T1D and body mass index ≥27.5 kg/m ETHICS AND DISSEMINATION: The trial protocol (V4.0/08.06.2022) was granted ethical approval by Cambridge East Research Ethics Committee (Ref: 21/EE/0014). The study will inform progression to a full-scale randomised controlled trial to test the efficacy of these programmes for patients with T1D and overweight and obesity. TRIAL REGISTRATION NUMBER: NCT04674384; Pre-results.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Insulin ResistanceMobile ApplicationsBlood GlucoseDietFeasibility StudiesHumansObesityOverweightQuality of LifeRandomized Controlled Trials as TopicState MedicineBlood Glucoseclinical trialsdiabetes & endocrinologynutrition & dietetics

Identifiers

PMID37474169
PMCPMC10360425
OpenAlexW4384923526

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.